REperfusion Therapy for Acute Ischemic STrOke Due to Large aRtEry Occlusion
The aim of the study was to establish a clinical and advanced imaging database of acute ischemic stroke patients treated with mechanical thrombectomy due to large vessel occlusion of anterior circulation within 24 hours from stroke onset in China, and to investigate the predictors and potential mechanisms of futile recanalization after mechanical thrombectomy.
• Older than 18 years;
• Perfusion imaging completed including CTA+CTP or MRA+PWI+DWI before thrombectomy
• Large vessel occlusion of cerebral anterior circulation (ICA, MCA-M1 or MCA-M2) confirmed by CTA or MRA, planned to receive or received stenting or aspiration thrombectomy
• Time intervals ≤ 24 hours from stroke onset to groin puncture.(fulfilled the inclusion of DAWN or DEFUSE 3 trial if the time intervals from stroke onset to groin puncture was ≥6 hours)
• mRS score ≤2 before admission
• Informed consent obtained for longitudinal enrolled patients, waived of consent for retrospectively included cases