Algorithm Development Through Artificial Intelligence for the Triage of Stroke Patients in the Ambulance With Electroencephalography

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Endovascular thrombectomy (EVT) enormously improves the prognosis of patients with large vessel occlusion (LVO) stroke, but its effect is highly time-dependent. Direct presentation of patients with an LVO stroke to an EVT-capable hospital reduces onset-to-treatment time by 40-115 minutes and thereby improves clinical outcome. Electroencephalography (EEG) may be a suitable prehospital stroke triage instrument for identifying LVO stroke, as differences have been found between EEG recordings of patients with an LVO stroke and those of suspected acute ischemic stroke patients with a smaller or no vessel occlusion. The investigators expect EEG can be performed in less than five minutes in the prehospital setting using a dry electrode EEG cap. An automatic LVO-detection algorithm will be the key to reliable, simple and fast interpretation of EEG recordings by ambulance paramedics. The primary objective of this study is to develop one or more novel AI-based algorithms (the AI-STROKE algorithms) with optimal diagnostic accuracy for identification of LVO stroke in patients with a suspected acute ischemic stroke in the prehospital setting, based on ambulant EEG data.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Suspected AIS, as assessed by the attending ambulance paramedic, or a known LVO stroke;

• Onset of symptoms or last seen well \< 24 hours before EEG acquisition;

• Age of 18 years or older;

• Written informed consent by patient or legal representative (deferred).

Locations
Other Locations
Netherlands
Amsterdam University Medical Centers, location AMC
RECRUITING
Amsterdam
Contact Information
Primary
Maritta N van Stigt, MSc
m.n.vanstigt@amterdamumc.nl
0031 20 566 8417
Backup
Jonathan M Coutinho, MD, PhD
j.coutinho@amsterdamumc.nl
0031 20 566 2004
Time Frame
Start Date: 2022-06-19
Estimated Completion Date: 2026-06
Participants
Target number of participants: 1192
Treatments
Experimental: Dry electrode cap EEG
All patients that are included in the study will undergo a dry electrode electroencephalography (EEG).
Related Therapeutic Areas
Sponsors
Leads: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

This content was sourced from clinicaltrials.gov