Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Upper Extremity Motor Function in Stroke Patients

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This clinical trial aims to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on upper extremity motor function in stroke patients. The main questions it seeks to answer are: 1. Whether repetitive transcranial magnetic stimulation (rTMS) has a positive effect on upper extremity motor function in stroke patients. 2. Which stimulation protocol (low frequency - LF or high-frequency - HF) has better outcomes for improving upper extremity motor function in stroke patients? Participants will receive 10 procedures of repetitive transcranial magnetic stimulation (rTMS) over two weeks. They will be randomly assigned into low-frequency, high-frequency rTMS groups or sham stimulation groups. Upper extremity motor function will be evaluated twice: before stimulation and 3-4 weeks after stimulation. Researchers will compare sham stimulation to see if it has the same or better outcomes for improving upper extremity motor function in stroke patients than real rTMS.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Ischemic stroke of the middle cerebral artery, confirmed by instrumental tests (CT, MRI).

• Acute hemiplegia/hemiparesis, hand motor deficit, muscle strength ≤ 4 points (as assessed by the Lovett scale).

• Time after the stroke before inclusion in the study is no more than 1 month.

• No severe deficit in cognitive functions.

Locations
Other Locations
Lithuania
Lithuanian University of Health Sciences
RECRUITING
Kaunas
Contact Information
Primary
Laura Petrusevičienė, MD
lciginskaite@gmail.com
+37064410732
Backup
Raimondas Savickas, Professor
raimondas.savickas@lsmuni.lt
+37068619797
Time Frame
Start Date: 2021-06-01
Estimated Completion Date: 2026-06-01
Participants
Target number of participants: 150
Treatments
Experimental: Low Frequency Experimental Group
Participants in this Arm will receive 10 sessions of Low Frequency (1 Hz) rTMS Participants in this Arm will receive 10 sessions of High Frequency (10 Hz) rTMS
Experimental: High Frequency Experimental Group
Participants in this Arm will receive 10 sessions of High Frequency (10 Hz) rTMS
Sham_comparator: Sham Stimulation Control Group
Participants in this Arm will receive 10 sessions of Sham rTMS
Related Therapeutic Areas
Sponsors
Leads: Lithuanian University of Health Sciences

This content was sourced from clinicaltrials.gov