Personalized Brain Functional Sector-guided Continuous Theta Burst Stimulation Therapy Targeting at Superior Temporal Gyrus for Aphasia After Ischemic Stroke: a RCT
The objective of this trial is to evaluate the effectiveness and safeness of continuous Theta Burst Stimulation (cTBS) over the right Superior Temporal Gyrus (STG), guided by personalized Brain Function Sector (pBFS) technology, on language function recovery in patients with post-ischemic stroke aphasia.
• The patient's age ranges from 35 to 75 years old (including 35 and 75 years old);
• Meet the diagnostic criteria for acute ischemic stroke (diagnosed according to the Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke written by the American Heart Association/American Stroke Association in 2019 and the Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2018 compiled by the Neurology Branch of the Chinese Medical Association in 2018), with lesions in the left hemisphere, a duration of ≥15 days and ≤3 months;
• Diagnosed as aphasia patient according to the Chinese version of Western Aphasia Battery (WAB), with a WAB-aphasia quotient of less than 93.8 points;
• First onset of stroke;
• Normal language function before the onset of stroke, and the patient's native language is Chinese with at least 6 years of education;
• Understand the trial and signed the informed consent form.