Pilot Study of the Characterization of Subacute Ischemic Cerebrovascular Accidents in the Region of the Middle Cerebral Artery by 3D Ultrasound Localization Microscopy (ULM) with a Research Ultrasound System and Non-marketed 2D Matrix Probe.

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this proof of concept study is to determine if the visualization of the middle cerebral artery and its perforators, through 3D transtemporal ultrasound imaging, is possible thanks to an off-line analysis by 3D ultrasound localization microscopy. Visualization of these vessels would allow us to conclude on the presence, or absence, of an ischemic stroke in the region of the middle cerebral artery. To answer the question asked, 20 participants who suffered a stroke will carry out a transtemporal ultrasound examination specifically for research in the 7 days following his stroke. The data obtained will be analyzed by the CNRS medical imaging laboratory, in order to characterize the presence of a stroke and to compare the data obtained with that of standard examinations (CT and MRI).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patient aged 18 and over

• Hospitalized patient with ischemic stroke in the deep territory of the middle cerebral artery

• Patient with lesion observable on MRI

• Patient included between 24 hours and 7 days after the ischemic stroke

• Patient with a temporal window which allows soundproofing of the polygon of Willis and the middle cerebral artery

• Patient having signed free, informed and written consent

• Patient affiliated to a social security system (excluding AME)

Locations
Other Locations
France
Hôpital Bichat
RECRUITING
Paris
Contact Information
Primary
Elena MESEGUER, Dr
elena.meseguer@aphp.fr
01.40.25.70.33
Backup
Marine CAMUS, Mrs
marine.camus2@aphp.fr
01.40.27.40.76
Time Frame
Start Date: 2024-03-22
Estimated Completion Date: 2025-02
Participants
Target number of participants: 20
Treatments
Experimental: Cohort group
Routine care + transtemporal ultrasound examination with contract product during hospitalization
Related Therapeutic Areas
Sponsors
Collaborators: Centre National de la Recherche Scientifique, France
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov