Intraarterial Verapamil for Neuroprotection in Ischemic Stroke
The purpose of this research study is to test an experimental procedure called intra-arterial delivery of verapamil in patients diagnosed with acute ischemic stroke. This study investigates the safety of intra-arterial delivery of verapamil, a drug used to treat vasospasm (spasm of a blood vessel), and how it affects recovery from stroke. Recruitment is limited to patients that have received mechanical thrombectomy as standard of care.
• Written informed consent
• 18 years of age and over
• Acute onset focal neurologic deficit consistent with acute ischemic stroke, or computed tomographic scan consistent with acute cerebral ischemia
• Candidate for mechanical thrombectomy procedure
• Onset of symptoms less than 8 hours
• Measurable neurologic deficit (NIHSS ≥4)
• Willingness to follow up with rehabilitation therapy
• Anticipated life expectancy of at least 3 months