Brain Connectivity Measured With High-density Electroencephalography: a Novel Neurodiagnostic Tool for Stroke

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Emerging scientific results show that disrupted functional connectivity in stroke can explain behavioral impairments and predict their recovery over time. However, no technique is yet available for widespread use in clinics to examine how neural synchronization in brain networks is altered in stroke patients. This is crucial to determine favorable prognostic factors and to define individualized rehabilitation protocols. Importantly, the investigators have successfully used high-density electroencephalography (hdEEG) in healthy individuals to measure neural synchronization in brain networks. In this project, the investigators will develop methods and tools based on hdEEG for assessing functional connectivity in stroke patients. These methods and tools will be employed to examine how neural changes occurring after brain lesions explain behavioral impairments. The project will open the way for the use of hdEEG at the patient's bedside, as a neurodiagnostic tool for stroke as well as other brain disorders.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• right or left hemisphere damage

• unilateral stroke

• compliance with magnetic resonance imaging (e.g., no claustrophobia)

⁃ • compliance with magnetic resonance imaging (e.g., no claustrophobia)

Locations
Other Locations
Italy
IRCCS San Camillo Hospital
RECRUITING
Venice
Contact Information
Primary
Dante Mantini
dante.mantini@hsancamillo.it
+39 0412207594
Backup
Giorgio Arcara
giorgio.arcara@hsancamillo.it
Time Frame
Start Date: 2020-06-11
Estimated Completion Date: 2025-02-02
Participants
Target number of participants: 170
Treatments
Other: stroke patients
Resting-state networks obtained through electroencephalography will be analyzed in a group of stroke patients.
Other: healthy participants
Resting-state networks obtained through electroencephalography will be analyzed in a group of healthy participants.
Related Therapeutic Areas
Sponsors
Leads: IRCCS San Camillo, Venezia, Italy

This content was sourced from clinicaltrials.gov