Construction of a Prediction Model for Severe Cardiovascular and Cerebrovascular Complications in Elderly Patients After Elective Non-cardiac Surgery: a Prospective Cohort Study
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
Severe cardiovascular and cerebrovascular complications, including cardiac death, non-fatal angina/myocardial infarction, non-fatal heart failure, stroke, severe arrhythmia, etc., are one of the main types of postoperative complications in elderly patients, and are also the main causes of perioperative death in elderly patients. With the aging population and the large proportion of elderly patients undergoing non-cardiac surgery, it is increasingly important to establish a prediction model for postoperative severe cardiovascular and cerebrovascular events in elderly patients undergoing noncardiac surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Healthy Volunteers: f
View:
• The subjects were patients with elective non-cardiac surgery;
• Older than 65 years;
• Patients signed informed consent.
Locations
Other Locations
China
Beijing Tsinghua Chang Gung Hospital
RECRUITING
Beijing
Contact Information
Primary
Huan Zhang, PhD
yhls01581@btch.edu.cn
17800822861
Backup
Haolin Yin, MD
374916066@qq.com
17738043809
Time Frame
Start Date: 2023-03-01
Estimated Completion Date: 2025-03-31
Participants
Target number of participants: 3000
Treatments
positive event group
The following complications occur within 3-7 days after surgery：~1. all-cause death;~2. non-fatal myocardial infarction/angina pectoris (new or recurring);~3. non-fatal heart failure (new onset or recurrence);~4. non-fatal cerebral infarction (new or reappeared);~5. new or recurrent malignant arrhythmias (ventricular tachycardia/ventricular fibrillation, atrial flutter/atrial fibrillation, hemodynamically unstable second/third degree atrioventricular block);
negative event group
The following complications did not occur within 3-7 days after surgery：~1. all-cause death;~2. non-fatal myocardial infarction/angina pectoris (new or recurring);~3. non-fatal heart failure (new onset or recurrence);~4. non-fatal cerebral infarction (new or reappeared);~5. new or recurrent malignant arrhythmias (ventricular tachycardia/ventricular fibrillation, atrial flutter/atrial fibrillation, hemodynamically unstable second/third degree atrioventricular block);
Related Therapeutic Areas
Sponsors
Leads: Beijing Tsinghua Chang Gung Hospital