Optimization of Time Parameters of Priming iTBS for Poststroke Motor Rehabilitation

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to identify the effect of different time intervals between continuous theta burst stimulation (cTBS) and intermittent theta burst stimulation(iTBS), on top of a standard robot-assisted training (RAT) for sensorimotor rehabilitation in patients with chronic stroke. Using electroencephalography (EEG) to explore potential sensorimotor neuroplasticity underying stroke.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: t
View:

• diagnosis of hemorrhagic or ischemic stroke using computed tomography (CT) or magnetic resonance imaging (MRI).

• the first-ever stroke with unilateral hemiplegia.

• 18-75 years old.

• chronic stroke ( ≥ 6 months).

• residual hemiparetic upper limb functional level in the Functional Test for the Hemiplegic Upper Extremity (FTHUE-HK) ≥ 2.

• can understand and read Chinese.

• signed informed consent.

Locations
Other Locations
Hong Kong Special Administrative Region
The Hong Kong Polytechnic University
RECRUITING
Hong Kong
The Hong Kong Polytechnic University
NOT_YET_RECRUITING
Hong Kong
Contact Information
Primary
Kenneth, Nai Kuen FONG, PhD
kenneth.fong@polyu.edu.hk
852 2766 6716
Backup
YOUXIN SUI, Master
youxin.sui@connect.polyu.hk
Time Frame
Start Date: 2024-10-01
Estimated Completion Date: 2025-10
Participants
Target number of participants: 65
Treatments
Experimental: cTBS primed iTBS with 3-minute interval
short interval(3min) between cTBS and iTBS
Experimental: cTBS primed iTBS with 10-minute interval
experimental interval(10min) between cTBS and iTBS
Experimental: cTBS primed iTBS with 20-minute interval
long interval(20min) between cTBS and iTBS
Sham_comparator: Non-primed iTBS
iTBS alone
Related Therapeutic Areas
Sponsors
Leads: The Hong Kong Polytechnic University

This content was sourced from clinicaltrials.gov