Multimodal Prognostic Assessment of Acute Ischemic Stroke Patients With Atrial Fibrillation: a Prospective, Multicenter, Observational Study (IAT-CLOSURE)
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The main purpose of this study is to investigate the safety and outcomes of different treatment strategies, including best medical therapy (OAC \[oral anticoagulation\], antiplatelet \[APT\]) and left atrial appendage closure \[LAAC\] in acute ischemic stroke (AIS) patients with atrial fibrillation (AF) based on multimodal assessment from combined brain and cardiologic work-up, and to optimize secondary prevention.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age \> 18 years old；
• Acute ischemic stroke with onset ≤ 14 days；
• Previously or during this hospitalization diagnosed with non-valvular atrial fibrillation;
• Informed consent obtained from the patient or his/her legal representative；
Locations
Other Locations
China
Jinan Central Hospital
RECRUITING
Jinan
Contact Information
Primary
Liqun Jiao
liqunjiao@sina.cn
13911224991
Backup
Guohai Su
suguohai1@126.com
19953193319
Time Frame
Start Date: 2024-11-15
Estimated Completion Date: 2029-05-31
Participants
Target number of participants: 1000
Treatments
Patients with acute ischemic stroke and atrial fibrillation
Adult patients with an acute ischemic stroke and atrial fibrillation will undergo a baseline work-up and cardiologic work-up. Baseline work-up includes admission 12-lead ECG，blood analysis, brain CT/MRI, brain CTA/MRA/vessel ultrasound. Cardiologic work-up includes prolonged ECG monitoring, echocardiography and cardiac CTA. Treatment will follow the current guidelines.
Related Therapeutic Areas
Sponsors
Leads: Jinan Central Hospital