Can Pulse Pressure Assessment at the Bedside Detect Low Values or Track Changes of Stroke Volume in Critically Ill Patients? The Multicenter, Cross-sectional, Observational, ANDROMEDA-PEGASUS Study
Status: Recruiting
Location: See all (3) locations...
Study Type: Observational
SUMMARY
The goal of this study is to assess the predictive capacity of pulse pressure to estimate stroke volume, as assessed by bedside echocardiography in critically ill patients. We hypothesize that pulse pressure will be able to adequately detect low values of stroke volume, and to track changes of stroke volume during commonly used dynamic cardiovascular interventions. Pulse pressure transduced from an arterial line will be measured simultaneously with left ventricular outflow tract velocity time integral in a broad range of critically ill patients. Ancillary clinical, hemodynamic and echocardiographic data will also be registered.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• 18 years
• Admitted to ICU
• Functioning arterial line in place
Locations
Other Locations
Brazil
Hospital Do Coracao
RECRUITING
São Paulo
Chile
Hospital Clinico UC Christus
RECRUITING
Santiago
Colombia
Fundacion Valle del Lili
RECRUITING
Santiago De Cali
Contact Information
Primary
Eduardo Kattan, MD, PhD
e.kattan@gmail.com
+56223543292
Backup
Glenn Hernandez, MD, PhD
glennguru@gmail.com
+56223543292
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2026-01-30
Participants
Target number of participants: 1500
Related Therapeutic Areas
Sponsors
Collaborators: Fundacion Clinica Valle del Lili, Hospital do Coracao, Erasmus Medical Center
Leads: Pontificia Universidad Catolica de Chile