Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease: a Randomised Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Age between 18 and 80 years old;

• Known patients with non-obstructive coronary artery disease (disease duration ≥2 years);

• Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations.

Locations
Other Locations
China
Research Institute Of Medical Imaging Jinling Hospital
RECRUITING
Nanjing
Contact Information
Primary
Longjiang Zhang, MD
kevinzhlj@163.com
13405833167
Time Frame
Start Date: 2025-02-28
Estimated Completion Date: 2028-12-30
Participants
Target number of participants: 3100
Treatments
Active_comparator: CCTA-based follow-up management group
The subjects will undergo routine clinical and laboratory examinations, as well as follow-up CCTA examinations to assess the progression of plaques and to recommend appropriate management, treatment, and follow-up based on the findings
Sham_comparator: clinical-based follow-up management group
The subjects will undergo routine clinical and laboratory examinations, and recommendations for appropriate management, treatment, and follow-up will be made based on the results.
Sponsors
Leads: Zhang longjiang,MD

This content was sourced from clinicaltrials.gov

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