COnCOmitaNt Pulse Field Ablation Based pUlmonary Vein Isolation and lefT Atrial Appendage Closure - The COCONUT Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

In patients with non-valvular AF, at high stroke risk, and who are ineligible for long-term oral anticoagulation LAAC could be an alternative to anticoagulation and safety and efficacy has been shown in several studies and registries.8 While PVI and LAAC are both conducted in the left atrium and share the same access route, a combined concomitant approach might be beneficial for patients but is not conventionally practiced. Due to significantly shorter procedures times and high safety profile PFA based catheter ablation may be advantageous for the combined approach of PVI and LAAC. We are performing a word-wide, retrospective, multicenter registry study focusing on patients with concomitant Farapulse PFA based PVI and LAAC (WATCHMAN Flx, Boston Scientific). To evaluate safety, efficacy and efficiency in a multicenter study the COCONUT study was conducted.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Indicatio for PVI and LAAC

Locations
Other Locations
Germany
Asklepios Klinik Altona
RECRUITING
Hamburg
Time Frame
Start Date: 2025-03-01
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 60
Treatments
Concomitant PVI plus LAAC
Sponsors
Leads: Asklepios proresearch

This content was sourced from clinicaltrials.gov