Efficacy of Trans-auricular Vagus Nerve Stimulation on Upper Extremity Motor Recovery in Stroke Survivors

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

The aim of this clinical trial is to determine if trans-auricular vagus nerve stimulation (taVNS) is effective in improving upper extremity function in stroke survivors. The primary objectives include: Investigating whether taVNS improves motor function in stroke survivors. The secondary objectives include: Assessing any potential side effects associated with the method. Investigating taVNS effects on daily routine functions and spasticity Researchers will conduct a comparative analysis between taVNS and a sham procedure (which mimics the stimulation without any actual effect) to assess its effectiveness. Participants in the trial will: Undergo taVNS combined with physical therapy or a sham procedure with physical therapy daily over a two-week period.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Patients aged between 18 and 75 years, with motor impairment in the upper extremity caused by unilateral ischemic or hemorrhagic stroke with stroke onset within the last five years.

Locations
Other Locations
Brazil
Federal University of Pernambuco
RECRUITING
Recife
Contact Information
Primary
DANIEL G DE MELO, MsC
gmelodaniel@gmail.com
+5581995173332
Backup
Gabriel Barreto, PhD
gbarretoantonino@gmail.com
83996106134
Time Frame
Start Date: 2025-08-01
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 30
Treatments
Experimental: Active transcutaneous vagus nerve stimulation stimulation
Sham_comparator: Sham transcutaneous vagus nerve stimulation stimulation
Related Therapeutic Areas
Sponsors
Collaborators: Fundação de Amparo à Ciência e Tecnologia de Pernambuco, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Leads: Universidade Federal de Pernambuco

This content was sourced from clinicaltrials.gov