Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2

Status: Recruiting
Location: See all (10) locations...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study is a prospective, multicenter, open-label, randomized controlled clinical trial. The investigators will apply albumin to the reperfusion treatment of patients with acute ischemic stroke in the anterior circulation. This study aims to verify the efficacy and safety of albumin combined with endovascular treatment in patients with anterior circulation acute ischemic stroke.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Age between 18 and 80 years;

• Acute ischemic stroke with indications for endovascular treatment within 24 hours of onset;

• Anterior circulation acute ischemic stroke, with acute occlusion of the responsible vessel located in the intracranial segment of the internal carotid artery, or the M1 or M2 segment of the middle cerebral artery;

• National Institute of Health Stroke Scale (NIHSS) score \>=6;

• Alberta Stroke Program Early CT Score (ASPECTS) \>=3 points;

• Modified Rankin Scale (mRS) score ≤1 before onset of the disease;

• Written informed consent provided by the patients or their legal relatives.

Locations
Other Locations
China
Xuanwu Hospital,Capital Medical University
RECRUITING
Beijing
Taihe County Hospital of Traditional Chinese Medicine
RECRUITING
Fuyang
Shanghai General Hospital Jiujuan Hospital
RECRUITING
Jiuquan
Jixi People's Hospital
RECRUITING
Jixi
Rizhao Hospital of Traditional Chinese Medicine
RECRUITING
Rizhao
Ningling County People's Hospital
RECRUITING
Shangqiu
Si County People's Hospital
RECRUITING
Suzhou
Laizhou People's Hospital
RECRUITING
Yantai
The First Affiliated Hospital of Henan University of Chinese Medicine
NOT_YET_RECRUITING
Zhengzhou
Zhongmou County People's Hospital
RECRUITING
Zhengzhou
Contact Information
Primary
Chuanjie Wu, MD
wuchuanjie@ccmu.edu.cn
010-83199439
Time Frame
Start Date: 2025-12-08
Estimated Completion Date: 2027-12-01
Participants
Target number of participants: 1192
Treatments
Experimental: Albumin combined with endovascular treatment group
Albumin combined with recommended endovascular treatment will be applied.
Active_comparator: Endovascular treatment group
Recommended endovascular treatment will be applied.
Related Therapeutic Areas
Sponsors
Leads: Capital Medical University

This content was sourced from clinicaltrials.gov