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Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2

Status: Recruiting
Location: See all (56) locations...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study is a prospective, multicenter, open-label, randomized controlled clinical trial. The investigators will apply albumin to the reperfusion treatment of patients with acute ischemic stroke in the anterior circulation. This study aims to verify the efficacy and safety of albumin combined with endovascular treatment in patients with anterior circulation acute ischemic stroke.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Age between 18 and 80 years;

• Acute ischemic stroke with indications for endovascular treatment within 24 hours of onset;

• Anterior circulation acute ischemic stroke, with acute occlusion of the responsible vessel located in the intracranial segment of the internal carotid artery, or the M1 or M2 segment of the middle cerebral artery;

• National Institute of Health Stroke Scale (NIHSS) score \>=6;

• Alberta Stroke Program Early CT Score (ASPECTS) \>=3 points;

• Modified Rankin Scale (mRS) score ≤4 before onset of the disease;

• Written informed consent provided by the patients or their legal relatives.

Locations
Other Locations
China
Susong County Hospital of Traditional Chinese Medicine
RECRUITING
Anqing
Baoding No. 1 Central Hospital
RECRUITING
Baoding
Xuanwu Hospital,Capital Medical University
RECRUITING
Beijing
People's Hospital of Bortala Mongol Autonomous Prefecture
RECRUITING
Bole
Bozhou People's Hospital
RECRUITING
Bozhou
Cenxi People's Hospital
RECRUITING
Cenxi
Changde First People's Hospital
RECRUITING
Changde
Feicheng Hospital of Shandong Yiyang Health Group
RECRUITING
Feicheng
Sanshui Hospital of Zhujiang Hospital, Southern Medical University
RECRUITING
Foshan
Taihe County Hospital of Traditional Chinese Medicine
RECRUITING
Fuyang
Fujian Medical University Union Hospital
RECRUITING
Fuzhou
Liuyang Jili Hospital
RECRUITING
Guankou
Guiyang Fourth People's Hospital
RECRUITING
Guiyang
Heyuan People's Hospital
RECRUITING
Heyuan
Huazhou People's Hospital
RECRUITING
Huazhou
Huiyang Sanhe Hospital
RECRUITING
Huizhou
Jiamusi University Hongda Hospital
RECRUITING
Jiamusi
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
RECRUITING
Jinan
Shanghai General Hospital Jiujuan Hospital
RECRUITING
Jiuquan
Jixi People's Hospital
RECRUITING
Jixi
People's Hospital of Bayingolin Mongolian Autonomous Prefecture
RECRUITING
Korla
Gansu Provincial Hospital
RECRUITING
Lanzhou
PLA Joint Logistic Support Force 940th Hospital
RECRUITING
Lanzhou
Linyi People's Hospital
RECRUITING
Linyi
Luoding People's Hospital
RECRUITING
Luoyang
Luoyang Central Hospital
RECRUITING
Luoyang
Ma'anshan People's Hospital
RECRUITING
Ma’anshan
Meishan Second People's Hospital
RECRUITING
Meishan
Donggang Central Hospital
RECRUITING
Nanchong
Pingdingshan Second People's Hospital
RECRUITING
Pingdingshan
Huize County People's Hospital
RECRUITING
Qujing
Rizhao Hospital of Traditional Chinese Medicine
RECRUITING
Rizhao
Ningling County People's Hospital
RECRUITING
Shangqiu
The First Affiliated Hospital of Shaoyang University
RECRUITING
Shaoyang
Daliuta Experimental Area Hospital of Shenmu City
RECRUITING
Shenmu
Taihe Hospital, Hubei University of Medicine
RECRUITING
Shiyan
Si County People's Hospital
RECRUITING
Suzhou
Kailuan General Hospital Linxi Hospital
RECRUITING
Tangshan
Tianmen First People's Hospital
RECRUITING
Tianmen
The First Affiliated Hospital of Xinxiang Medical University
RECRUITING
Weihui
Wuhu Second People's Hospital
RECRUITING
Wuhu
Wuwei People's Hospital
RECRUITING
Wuhu
Yan'an University Xianyang Hospital
RECRUITING
Xianyang
Xuzhou Cancer Hospital
RECRUITING
Xuzhou
Laizhou People's Hospital
RECRUITING
Yantai
PLA Joint Logistic Support Force 970th Hospital
RECRUITING
Yantai
Yiyang Central Hospital
RECRUITING
Yiyang
Yuncheng Central Hospital
RECRUITING
Yuncheng
Zhangzhou Hospital
RECRUITING
Zhangzhou
The First Affiliated Hospital of Henan University of Chinese Medicine
NOT_YET_RECRUITING
Zhengzhou
Zhengzhou Central Hospital Affiliated to Zhengzhou University
RECRUITING
Zhengzhou
Zhongmou County People's Hospital
RECRUITING
Zhengzhou
Shenqiu County People's Hospital
RECRUITING
Zhoukou
Xihua County People's Hospital
RECRUITING
Zhoukou
Zhoukou Central Hospital
RECRUITING
Zhoukou
Yiyuan County People's Hospital
RECRUITING
Zibo
Contact Information
Primary
Chuanjie Wu, MD
wuchuanjie@ccmu.edu.cn
010-83199439
Time Frame
Start Date: 2025-12-18
Estimated Completion Date: 2027-12-01
Participants
Target number of participants: 1192
Treatments
Experimental: Albumin combined with endovascular treatment group
Albumin combined with recommended endovascular treatment will be applied.
Active_comparator: Endovascular treatment group
Recommended endovascular treatment will be applied.
Related Therapeutic Areas
Sponsors
Leads: Capital Medical University

This content was sourced from clinicaltrials.gov