Longitudinal Study of Intra-Uterine Growth Restriction (IUGR)

Status: Recruiting
Location: See location...
Intervention Type: Radiation, Procedure, Behavioral
Study Type: Observational
SUMMARY

The investigation will employ a longitudinal approach in which every fetus diagnosed to be SGA (Small for Gestational Age ) will be studied at frequent intervals with sophisticated imaging techniques to assess subtle physiologic changes in the brain, heart, and placenta over time. These findings will be correlated with neurological and cardiovascular function in the newborn and early childhood. This research initiative should yield diagnostic and therapeutic templates that will improve the quality of life of IUGR babies in addition to providing important information that will better inform current diagnostic practices.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• Patients with diagnosed SGA by an ultrasound estimated fetal weight (EFW) of less than the 10th percentile or a fetal abdominal circumference of less than the 5th percentile will be included in the study at the time of their first examination.

Locations
United States
Colorado
University of Colorado Denver Anschutz Medical Campus
RECRUITING
Aurora
Contact Information
Primary
Emma Peek, BS
emma.peek@cuanschutz.edu
Time Frame
Start Date: 2015-04
Estimated Completion Date: 2025-12
Participants
Target number of participants: 200
Treatments
Small for Gestational Age Pregancies (controls)
Small for gestational age (SGA) pregnancies that do not develop IUGR will be considered controls. Each subject will have an ultrasound, MRI, maternal blood and cord blood collection, placental analysis, neurological function assessments (infant), and body fat measurements (infant).
IUGR Pregnancies (cases)
Small for gestational age (SGA) pregnancies that do develop IUGR will be considered cases. Each subject will have an ultrasound, MRI, maternal blood and cord blood collection, placental analysis, neurological function assessments (infant), and body fat measurements (infant).
Related Therapeutic Areas
Sponsors
Collaborators: The Perelman Family Foundation
Leads: University of Colorado, Denver

This content was sourced from clinicaltrials.gov