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Comparative Effects of Functional Electrical Stimulation and Mirror Therapy for Foot Clearance Among Patients With Sub-acute Stroke

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to evaluate the effectiveness of two rehabilitation techniques- Functional Electrical Stimulation (FES) and Mirror Therapy (MT)-in improving motor recovery among stroke survivors. Stroke often results in long-term impairments, particularly in foot clearance, which is critical for daily activities. Although current rehabilitation strategies help, more effective solutions are needed to enhance recovery. Participants, aged 18- 85 years old with subacute stroke and foot clearance impairments, will be randomized into two groups: Group A will receive functional electrical stimulation (FES) with routine physical therapy; and Group B will receive mirror therapy (MT) with routine physical therapy. The interventions will take place three times a week for 4 weeks, and participants will undergo motor function assessments, including the Fugl-Meyer Assessment and Functional Independence Measure, before and after the intervention. The study will compare the effects of each intervention on motor recovery, specifically focusing on tibialis anterior function and motor control. The findings could lead to improved rehabilitation protocols, offering stroke survivors better therapeutic options and enhancing their quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
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• Patient aged 18-85 years of age, who experienced stroke within ≤6 months.

• The Fugl-Meyer motor assessment of lower extremity (FMA-LE) was conducted by physiotherapist in the hospital, and score required to be ≥ 20 points.

• Participants possessed healthy nerves, neuromuscular junctions, muscles tissues, and a sufficient range of motion in dorsiflexor and plantarflexion.

• The subjects could walk independently on a treadmill for at least 2 min without without experiencing adverse reaction to FES.

• Patients who received more 24 scores on Mini Mental State Exam and could comprehend and follow the information researcher provides.

• No orthopedic diseases in upper and lower extremities.

• Patients with functional ambulation classification (FAC) score of 3 or 4 were included (FAC is a scale of 0-5, where 3 indicates supervision or standby guarding and 4 indicates independent on level surfaces.

• Patients with inadequate ankle dorsiflexion during the swing phase of gait.

• Patients with adequate minimal stability at the ankle during stance with stimulation.

Locations
Other Locations
Pakistan
Lahore University of Biological and Applied Sciences
RECRUITING
Lahore
Contact Information
Primary
Nabeela Dawood
nabeela.dawood@ubas.edu.pk
+923315337445
Time Frame
Start Date: 2026-01-22
Estimated Completion Date: 2026-06-27
Participants
Target number of participants: 38
Treatments
Experimental: Group A (Functional Electrical Stimulation and Routine Physical Therapy)
Functional Electrical Stimulation (FES) in combination with Routine Physical Therapy.~The interventions will be administered three times per week over a four-week period. Each session will last 50 minutes.~Functional Electrical Stimulation will be applied to the affected lower limb, primarily targeting muscles responsible for ankle dorsiflexion, to facilitate improved foot clearance during gait. In addition to FES, participants will undergo Routine Physical Therapy consisting of stretching exercises, strengthening exercises, and repeated task-oriented gait training aimed at improving functional ambulation.~Routine Physical Therapy will be provided for 20 minutes per session, while FES will be applied for 30 minutes, making a total session duration of 50 minutes.~This arm aims to assess the effects of neuromodulation through peripheral electrical stimulation on foot clearance and gait performance in sub-acute stroke patients.
Active_comparator: Group B (Mirror Therapy and Routine Physical Therapy)
Group B will receive Mirror Therapy in combination with Routine Physical Therapy.~The interventions will be administered three times per week over a four-week period, with each session lasting 50 minutes.~Mirror Therapy will involve participants performing movements of the unaffected lower limb while observing its reflection in a mirror placed in the sagittal plane, creating the illusion that the affected limb is moving normally. This intervention is intended to enhance sensory feedback and promote motor recovery through visual input.~Alongside Mirror Therapy, participants will receive Routine Physical Therapy consisting of stretching, strengthening exercises, and repeated task-oriented gait training.~Routine Physical Therapy will be provided for 20 minutes, while Mirror Therapy will be conducted for 30 minutes per session, resulting in a total treatment duration of 50 minutes.~This arm aims to evaluate the effects of sensory augmentation through visual feedback on foot clearance and
Related Therapeutic Areas
Sponsors
Leads: Lahore University of Biological and Applied Sciences

This content was sourced from clinicaltrials.gov