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PROMISE Registry: PROspective Study on Management of Ischemic Stroke Secondary to mEvo Registry

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Investigators are conducting a real world, observational, prospective, multicenter study to better understand treatment for patients with MeVo and distal vessel occlusions in the U.S post publication of recent MeVO trials.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Acute ischemic stroke clinically eligible for immediate EVT

• Age ≥18 - 85 years of age

• Time from onset (or last-seen-well) to 24 hours

• Disabling stroke defined as follows:

• A. Baseline National Institutes of Health Stroke Scale (NIHSS) score \>5 B. Baseline NIHSS 3-5 with disabling deficit (e.g., hemianopia, aphasia, loss of hand function) as determined and agreed upon by two physicians in context of the patient's life

• Confirmed treatable MeVO based on neurovascular non-invasive imaging (CTA or MRA), at one or more of the following locations: M2 or M3 segment, A2 or A3 segment, P1, P2 or P3 segment

• Informed consent: Within the first 72 hours after inclusion in the study

• ASPECTS ≥5

• mRS≤2

Locations
United States
Indiana
IU Health Neuroscience Center
RECRUITING
Indianapolis
Contact Information
Primary
Kaustubh Limaye, MD, FAHA
klimaye@iu.edu
317-963-7378
Time Frame
Start Date: 2026-07-11
Estimated Completion Date: 2030-07-11
Participants
Target number of participants: 652
Treatments
Endovascular Treatment
Intra-arterial Treatment
Medical Management
Intravenous Thrombolytic
Related Therapeutic Areas
Sponsors
Collaborators: phenox Inc.
Leads: Indiana University

This content was sourced from clinicaltrials.gov

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