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A Novel Approach to Implementing Constraint-Induced Movement Therapy in Stroke Rehabilitation

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn how a partially self-supervised constraint-induced movement therapy (sCIMT) program in adults with arm and hand weakness will work after stroke. This study will look at whether the program can help people improve the use of their arm and hand after a stroke while requiring less time with a therapist. The main questions it aims to answer are: * Does the sCIMT program help people use their affected arm and hand better - after a stroke? * Do participants feel that the sCIMT program is useful, easy to follow, and a good fit for their recovery needs? * Does taking part in the sCIMT program improve participants' quality of life and daily well-being? Participants will: * Take part in a therapy program 5x/week for 2 weeks. The program is designed to help improve the use of the arm and hand affected by stroke. * Wear a mitt on the stronger hand during certain practice activities to encourage use of the weaker hand. * Complete surveys and tests before and after the program to measure arm and hand use, experiences with the program, and quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Sustained a first-time ischemic or hemorrhagic stroke ≥2 weeks prior to study enrollment

• Age ≥18 and ≤85

• Moderate UE hemiparesis as defined by a score ≥13 and ≤47 on the modified UE section of the Fugl-Meyer Assessment (60-point scale with no reflex testing)

• Ability to actively extend impaired wrist ≥10 degrees

• UE strength and active range of motion within functional limits on the non-hemiparetic side

• Ability to follow two-step commands (visual or verbal) as determined by the clinical investigator

• Nonuse of the more impaired UE as evidenced by an average score ≤2.5 on the Motor Activity Log Amount of Use Scale.

Locations
United States
Ohio
Ohio State University
RECRUITING
Columbus
Contact Information
Primary
Peyton Miller
peyton.miller@osumc.edu
380-283-5825
Backup
Lauren Wengerd
lauren.wengerd@osumc.edu
Time Frame
Start Date: 2026-07-29
Estimated Completion Date: 2027-12
Participants
Target number of participants: 12
Treatments
Experimental: Self-Supervised Constraint-Induced Movement Therapy
Participants will receive self-supervised constraint-induced movement therapy (sCIMT) to improve upper extremity function following stroke. The intervention consists of up to 30 hours of rehabilitation delivered over 2 weeks (3-hour sessions, up to 5 sessions per week). During each session, participants alternate between brief periods of one-to-one therapist-guided training and self-supervised task practice, with approximately one-third of treatment time provided individually by a therapist and two-thirds completed independently. Treatment activities include task-oriented functional and non-functional upper extremity exercises designed to promote motor recovery and use of the affected arm.
Related Therapeutic Areas
Sponsors
Leads: Ohio State University

This content was sourced from clinicaltrials.gov