Comparison of Unimanual Versus Bimanual Motor Skill Learning (Proximal and Distal) After Stroke by Means of Robotics (REA²Plan® and Dextrain®) and Multimodal Brain Imaging (VLSM, DTI, NODDI, DIAMOND)
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To test the capacity of healthy individuals, chronic and acute stroke patients to learn and retain a complex unimanual or bimanual motor skill, trained on the neurorehabiliation robot REAplan® et the Dextrain® device. The goals are (1) to compare head-to-head bimanual versus unimanual motor learning (in the proximal and distal upper limb, UL) during the acute - early subactue stage of stroke with robotics and (2) to identify the neural substrates associated with (and deficits in) unimanual versus bimanual motor control (proximal and distal) after stroke by means of multimodal brain imaging.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 90
Healthy Volunteers: t
View:
• acute stroke (between day 2 and day 21 post-stroke) or chronic stroke (\>6 mois)
• aged 40-90 years
• with a single demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging
• 40-90 years
Locations
Other Locations
Belgium
CHU UCL Namur
RECRUITING
Yvoir
Contact Information
Primary
Yves Vandermeeren, MD, PhD
yves.vandermereen@uclouvain.be
+32 (0)81 42 33 21
Backup
Laura Santelé, MSc
laura.santele@uclouvain.be
+32 (0)81 42 34 91
Time Frame
Start Date:2026-05-18
Estimated Completion Date:2031-12-31
Participants
Target number of participants:200
Treatments
Experimental: Bimanual tasks
Training on the REAplan® robot with a serious game based on proximal motor skill learning (MSkL) with the bimanual version of the Circuit task and training on the Dextrain® Manipulandum with a serious game based on the distal MSkL with a bimanual version of the Targeting task.
Experimental: Unimanual tasks
Training on the REAplan® robot with a serious game based on proximal motor skill learning (MSkL) with the unimanual version of the Circuit task and training on the Dextrain® Manipulandum with a serious game based on the distal MSkL with a unimanual version of the Targeting task.