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Learn About Cytomegalic Inclusion Disease

What is the definition of Cytomegalic Inclusion Disease?
Cytomegalic inclusion disease is an infection in newborns caused by the cytomegalovirus. When a pregnant woman has an active cytomegalovirus infection during pregnancy or breastfeeding, the virus can be passed to their babies. Cytomegaloviruses are also known as salivary gland viruses.
What are the symptoms of Cytomegalic Inclusion Disease?
Symptoms of cytomegalic inclusion disease in the newborn can range from no symptoms to severe symptoms affecting the central nervous system, liver, spleen, and possibly causing developmental disabilities. Other symptoms of severe cytomegalic inclusion disease in infants may include hemorrhagic anemia, low birth weight, fever, hepatitis, yellowing of the skin and whites of the eyes, rash, purple skin blotches, pneumonia, enlarged liver and/or spleen, decreased blood platelets, eye inflammation, abnormally small head, calcification of the ventricles of the brain, developmental motor defects, cognitive disabilities, spastic paralysis, blindness, deafness, and seizures.
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What are the current treatments for Cytomegalic Inclusion Disease?
There is currently no cure for cytomegalic inclusion disease. Treatment for cytomegalic inclusion disease is focused on controlling symptoms. Treatments for cytomegalic inclusion disease include antiviral drugs, such as gancicolovir and foscarnet; azathioprine; prednisone; basiliximab; and miconazole.
Who are the top Cytomegalic Inclusion Disease Local Doctors?
Sallie R. Permar
Pediatric Infectious Disease | Infectious Disease | Pediatrics
Pediatric Infectious Disease | Infectious Disease | Pediatrics
2100 Erwin Rd, 
Durham, NC 
 60.0 mi

Sallie Permar is a Pediatric Infectious Disease specialist and an Infectious Disease provider in Durham, North Carolina. Dr. Permar has been practicing medicine for over 21 years and is rated as an Elite provider by MediFind in the treatment of Cytomegalic Inclusion Disease. Her top areas of expertise are Cytomegalovirus Infection, Congenital Cytomegalovirus, Cytomegalic Inclusion Disease, and HIV/AIDS.

Nephrology | Hospital Medicine
Nephrology | Hospital Medicine

Duke Health Integrated Practice Inc

1234 Huffman Mill Rd, 
Burlington, NC 
 84.2 mi
Accepting New Patients
Offers Telehealth

Matthew Ellis is a Nephrologist and a Hospital Medicine provider in Burlington, North Carolina. Dr. Ellis and is rated as a Distinguished provider by MediFind in the treatment of Cytomegalic Inclusion Disease. His top areas of expertise are Cytomegalic Inclusion Disease, Cytomegalovirus Infection, End-Stage Renal Disease (ESRD), and Nephrosclerosis. Dr. Ellis is currently accepting new patients.

 
 
 
 
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Rachel A. Miller
Infectious Disease
Infectious Disease

Duke Health Integrated Practice Inc

2301 Erwin Rd, 
Durham, NC 
 60.3 mi
Accepting New Patients
Offers Telehealth

Rachel Miller is an Infectious Disease provider in Durham, North Carolina. Dr. Miller has been practicing medicine for over 36 years and is rated as an Advanced provider by MediFind in the treatment of Cytomegalic Inclusion Disease. Her top areas of expertise are Cytomegalovirus Infection, Cytomegalic Inclusion Disease, Nocardiosis, and Actinomycosis. Dr. Miller is currently accepting new patients.

What are the latest Cytomegalic Inclusion Disease Clinical Trials?
A Phase I Pharmacokinetic and Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus Disease

Summary: This is a Phase 1 single-arm open-label study of letermovir in neonates with symptomatic congenital Cytomegalovirus (CMV) disease. There will be two groups enrolled. Group 1 will be comprised of 4 subjects. Following documentation study inclusion and signing of informed consent, Group 1 subjects will receive one dose of oral letermovir (Study Day 0), using the dose bands. A full pharmacokinetics (...

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Cytomegalovirus (CMV) Vaccines: Reinfection and Antigenic Variation

Summary: The objectives of the protocol are to determine if a structured cognitive-behavioral interventional counseling of pregnant women can limit acquisition of human cytomegalovirus (HCMV) during pregnancy that we believe, will in turn decrease the incidence of congenital HCMV infections in this highly seroimmune population. Previously, investigators have demonstrated the success of a similar approach i...