Cytomegalic Inclusion Disease
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Learn About Cytomegalic Inclusion Disease

What is the definition of Cytomegalic Inclusion Disease?
Cytomegalic inclusion disease is an infection in newborns caused by the cytomegalovirus. When a pregnant woman has an active cytomegalovirus infection during pregnancy or breastfeeding, the virus can be passed to their babies. Cytomegaloviruses are also known as salivary gland viruses.
What are the symptoms of Cytomegalic Inclusion Disease?
Symptoms of cytomegalic inclusion disease in the newborn can range from no symptoms to severe symptoms affecting the central nervous system, liver, spleen, and possibly causing developmental disabilities. Other symptoms of severe cytomegalic inclusion disease in infants may include hemorrhagic anemia, low birth weight, fever, hepatitis, yellowing of the skin and whites of the eyes, rash, purple skin blotches, pneumonia, enlarged liver and/or spleen, decreased blood platelets, eye inflammation, abnormally small head, calcification of the ventricles of the brain, developmental motor defects, cognitive disabilities, spastic paralysis, blindness, deafness, and seizures.
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What are the current treatments for Cytomegalic Inclusion Disease?
There is currently no cure for cytomegalic inclusion disease. Treatment for cytomegalic inclusion disease is focused on controlling symptoms. Treatments for cytomegalic inclusion disease include antiviral drugs, such as gancicolovir and foscarnet; azathioprine; prednisone; basiliximab; and miconazole.
Who are the top Cytomegalic Inclusion Disease Local Doctors?
Emily A. Blumberg
Elite in Cytomegalic Inclusion Disease
Infectious Disease
Elite in Cytomegalic Inclusion Disease
Infectious Disease

MacGregor Infection Medicine And Travel Program

3400 Civic Center Boulevard, South Pavilion, 4th Floor, 
Philadelphia, PA 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Emily Blumberg is an Infectious Disease provider in Philadelphia, Pennsylvania. Dr. Blumberg is rated as an Elite provider by MediFind in the treatment of Cytomegalic Inclusion Disease. Her top areas of expertise are Cytomegalovirus Infection, Cytomegalic Inclusion Disease, HIV/AIDS, Kidney Transplant, and Liver Transplant. Dr. Blumberg is currently accepting new patients.

Mark Schleiss
Elite in Cytomegalic Inclusion Disease
Infectious Disease
Elite in Cytomegalic Inclusion Disease
Infectious Disease

Office

2001 6th St SE, 
Minneapolis, MN 
Languages Spoken:
English

Mark Schleiss is an Infectious Disease provider in Minneapolis, Minnesota. Dr. Schleiss is rated as an Elite provider by MediFind in the treatment of Cytomegalic Inclusion Disease. His top areas of expertise are Congenital Cytomegalovirus, Cytomegalovirus Infection, Cytomegalic Inclusion Disease, Cryptococcosis, and Myringotomy.

 
 
 
 
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Robin K. Avery
Elite in Cytomegalic Inclusion Disease
Infectious Disease
Elite in Cytomegalic Inclusion Disease
Infectious Disease

Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville

10751 Falls Road, Falls Concourse STE 412, Falls Concourse STE 412, 
Lutherville, MD 
Languages Spoken:
English
Offers Telehealth

Dr. Robin Avery is an infectious disease physician who joined the Johns Hopkins faculty in 2012, with two decades of experience in transplant infectious disease. She is a past chair of the American Society of Transplantation (AST) Infectious Disease Community of Practice, was a co-editor of the first edition of the AST ID Guidelines, and serves on a Guidelines Committee for the Infectious Disease Society of America (IDSA) on immunizations in the immunocompromised host. She was the founding head of the Transplant Infectious Disease Section at the Cleveland Clinic and served as the founding director of the Cleveland Clinic Transplant ID Special Fellowship, authoring a curriculum that served as the basis for curricula later endorsed by the AST and IDSA. Her clinical and research interests include pre-transplant donor and recipient evaluation, and prevention and treatment of post-transplant infections, particularly transplant-associated viruses, viral load monitoring, novel therapies for CMV, hypogammaglobulinemia, immunizations, and strategies for safer living post-transplant. She has a strong interest in patient education and co-authored the script for a video designed to educate patients on decreasing post-transplant infection risks. Dr. Avery is rated as an Elite provider by MediFind in the treatment of Cytomegalic Inclusion Disease. Her top areas of expertise are Cytomegalic Inclusion Disease, Cytomegalovirus Infection, COVID-19, and Sepsis.

What are the latest Cytomegalic Inclusion Disease Clinical Trials?
A Phase I Pharmacokinetic and Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus Disease

Summary: This is a Phase 1 single-arm open-label study of letermovir in neonates with symptomatic congenital Cytomegalovirus (CMV) disease. There will be two groups enrolled. Group 1 will be comprised of 4 subjects. Following documentation study inclusion and signing of informed consent, Group 1 subjects will receive one dose of oral letermovir (Study Day 0), using the dose bands. A full pharmacokinetics (...

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A Clinical Study on the Efficacy of Extended Letermovir Prophylaxis to Prevent CMV Reactivation in High-Risk Chinese Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Summary: After allogeneic hematopoietic stem cell transplantation (allo-HSCT), recipients are immunocompromised and at increased risk of complications, including cytomegalovirus (CMV) infection. International clinical guidelines for the management of CMV infection post-allo-HSCT recommend three main strategies: minimizing infection risk, prevention, and preemptive therapy. However, traditional antiviral ag...