What is the definition of D-Minus Hemolytic Uremic Syndrome?

D-minus (diarrhea negative) hemolytic uremic syndrome is an extremely rare, progressive genetic disease characterized by low levels of red blood cells (hemolytic anemia), low platelets (thrombocytopenia), and an inability of the kidneys to process waste products from the blood (uremia).

What are the symptoms for D-Minus Hemolytic Uremic Syndrome?

Symptoms of D-minus hemolytic uremic syndrome may include malaise, fatigue, irritability, lethargy, decreased urine, paleness, scattered bruising, gastrointestinal bleeding, high blood pressure, headaches, double vision, facial paralysis, stroke, seizures, coma, fluid in the lungs, enlarged heart, and kidney failure.

What are the current treatments for D-Minus Hemolytic Uremic Syndrome?

Treatment for D-minus hemolytic uremic syndrome may include intravenous nutrition and fluid replacement, kidney or peritoneal dialysis, blood transfusion, vasodilators, medications, such as eculizumab and ultomiris (favulizumab-cwyz), plasma exchange (plasmapheresis), immunosuppressive therapy, or kidney transplant.
  • Condition: Mutation in Complement Factor B in Atypical Hemolytic Uremic Syndrome Patient
  • Journal: Frontiers in immunology
  • Treatment Used: Combined Liver-Kidney Transplantation
  • Number of Patients: 1
  • Published —
This case report describes a four-month-old boy with atypical hemolytic uremic syndrome (aHUS) treated with combined liver-kidney transplantation.
  • Journal: Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)
  • Published —
Anti-Factor H Antibody-Associated Atypical Hemolytic Uremic Syndrome: A Case Report.