Deep Vein Thrombosis
Symptoms, Doctors, Treatments, Advances & More

Learn About Deep Vein Thrombosis

What is the definition of Deep Vein Thrombosis?

Deep vein thrombosis (DVT) is a condition that occurs when a blood clot forms in a vein deep inside a part of the body. DVT mainly affects the large veins in the lower leg and thigh, but can occur in other deep veins, such as in the arms and pelvis. DVT most often affects only one side of the body.

What are the alternative names for Deep Vein Thrombosis?

DVT; Blood clot in the legs; Thromboembolism; Post-phlebitic syndrome; Post-thrombotic syndrome; Venous - DVT

What are the causes of Deep Vein Thrombosis?

DVT is most common in adults over age 60. But it can occur at any age. When a clot breaks off and moves through the bloodstream, it is called an embolism. An embolism can get stuck in the blood vessels in the brain, lungs, heart, or another area, leading to severe damage.

Blood clots may form when something slows or changes the flow of blood in the veins.

Risk factors include:

  • A pacemaker catheter that has been passed through a vein in the groin
  • Bed rest or sitting in one position for too long, such as plane or car travel
  • Family history of blood clots
  • Fractures in the pelvis or legs
  • Giving birth within the last 6 months
  • Pregnancy
  • Obesity
  • Recent surgery (most commonly hip, knee, or female pelvic surgery)
  • Too many blood cells being made by the bone marrow, causing the blood to be thicker than normal (polycythemia vera)
  • Having an indwelling (long-term) catheter in a blood vessel
  • Age greater than 60

Blood is more likely to clot in someone who has certain problems or disorders, such as:

  • Cancer
  • Certain autoimmune disorders, such as lupus
  • Cigarette smoking
  • Conditions that make it more likely to develop blood clots
  • Taking estrogens or birth control pills (this risk is even higher with smoking)

Sitting for long periods when traveling can increase the risk for DVT. This is most likely when you also have one or more of the risk factors listed above.

What are the symptoms of Deep Vein Thrombosis?

DVT mainly affects the large veins in the lower leg and thigh, most often on one side of the body. The clot can block blood flow and cause:

  • Redness of the skin
  • Skin that feels warm to the touch
  • Swelling (edema) of a leg or arm
  • Pain or tenderness in a leg or arm
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What are the current treatments for Deep Vein Thrombosis?

Your provider will give you medicine to thin your blood (called an anticoagulant). This will keep more clots from forming or old ones from getting bigger.

Heparin is often the first medicine you will receive.

  • If heparin is given through a vein (IV), you must stay in the hospital. However, most people can be treated without staying in the hospital.
  • Low molecular weight heparin can be given by injection under your skin once or twice a day. You may not need to stay in the hospital as long, or at all, if you are prescribed this type of heparin.

One type of blood-thinning medicine called warfarin (Coumadin or Jantoven) may be started along with heparin. Warfarin is taken by mouth. It takes several days to fully work.

Another class of blood thinners are called direct oral anticoagulants (DOAC), including:

  • Apixaban (Eliquis)
  • Dabigatran (Pradaxa)
  • Edoxaban (Savaysa)
  • Rivaroxaban (Xarelto)

These medicines work in a similar way to heparin and can be used right away in place of heparin. Your provider will decide which medicine is right for you.

You will most likely take a blood thinner for at least 3 months. Some people take it longer, or even for the rest of their lives, depending on their risk for another clot and for bleeding.

When you are taking a blood thinning medicine, you are more likely to bleed, even from activities you have always done. If you are taking a blood thinner at home:

  • Take the medicine just the way your provider prescribed it.
  • Ask your provider what to do if you miss a dose.
  • Ask your provider if you need to take an oral medicine on an empty stomach.
  • Get blood tests as advised by your provider to make sure you are taking the right dose. These tests are usually needed with people who are taking warfarin.
  • Find out how to watch for problems caused by the medicine.

In rare cases, you may need a procedure instead of or in addition to anticoagulants. These may involve:

  • Placing a filter in the body's largest vein to prevent blood clots from traveling to the lungs
  • Removing a large blood clot from the vein or injecting clot-busting medicines

Follow any other instructions you are given to treat your DVT.

Who are the top Deep Vein Thrombosis Local Doctors?
Elite in Deep Vein Thrombosis
Internal Medicine
Elite in Deep Vein Thrombosis
Internal Medicine

University Hospitals

11100 Euclid Ave, 
Cleveland, OH 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Natalie Evans is a primary care provider, practicing in Internal Medicine in Cleveland, Ohio. Dr. Evans is rated as an Elite provider by MediFind in the treatment of Deep Vein Thrombosis. She is also highly rated in 42 other conditions, according to our data. Her clinical expertise encompasses Deep Vein Thrombosis, Pulmonary Embolism, Superficial Thrombophlebitis, Embolectomy, and Thrombectomy. Dr. Evans is currently accepting new patients.

Distinguished in Deep Vein Thrombosis
Geriatrics | Internal Medicine
Distinguished in Deep Vein Thrombosis
Geriatrics | Internal Medicine
Referral may be required

Suburban Geriatrics Inc

2901 Jolly Road, 
Plymouth Meeting, PA 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Robert Pearlstein is a primary care provider, practicing in Geriatrics and Internal Medicine in Plymouth Meeting, Pennsylvania. Dr. Pearlstein is rated as a Distinguished provider by MediFind in the treatment of Deep Vein Thrombosis. He is also highly rated in 180 other conditions, according to our data. His clinical expertise encompasses Dementia, Alzheimer's Disease, Painful Swallowing, Gastrostomy, and Endoscopy. Dr. Pearlstein is board certified in  . Dr. Pearlstein is currently accepting new patients.

 
 
 
 
Learn about our expert tiers
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Elite in Deep Vein Thrombosis
Vascular Surgery | General Surgery
Elite in Deep Vein Thrombosis
Vascular Surgery | General Surgery
Referral may be required

Vascular Surgery Clinic

1425 E Ann St, Floor 3 Reception B, 
Ann Arbor, MI 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Peter Henke is a Vascular Surgeon and a General Surgeon practicing medicine in Ann Arbor, Michigan. Dr. Henke is rated as an Elite provider by MediFind in the treatment of Deep Vein Thrombosis. He is also highly rated in 31 other conditions, according to our data. His clinical expertise encompasses Mesenteric Venous Thrombosis, Deep Vein Thrombosis, Peripheral Artery Disease, Aneurysm Repair, and Carotid Artery Surgery. Dr. Henke is board certified in Surgery and Vascular Surgery. Dr. Henke is currently accepting new patients.

What is the outlook (prognosis) for Deep Vein Thrombosis?

DVT often goes away without a problem, but the condition can return. The symptoms can appear right away or you may not develop them for one or more years afterward. Wearing compression stockings during and after the DVT may help prevent this problem.

What are the possible complications of Deep Vein Thrombosis?

Complications of DVT may include:

  • Pulmonary embolism (which may be fatal)
  • Constant or intermittent pain and swelling (post-phlebitic or post-thrombotic syndrome)
  • Varicose veins
  • Non-healing skin ulcers (less common)
  • Changes in skin color
When should I contact a medical professional for Deep Vein Thrombosis?

Contact your provider if you have symptoms of DVT.

Go to the emergency room or call the local emergency number (such as 911) if you have DVT and you develop:

  • Chest pain
  • Coughing up blood
  • Difficulty breathing
  • Fainting
  • Loss of consciousness
  • Other severe symptoms
How do I prevent Deep Vein Thrombosis?

To prevent DVT:

  • Move your legs often during long plane trips, car trips, and other situations in which you are sitting or lying down for long periods.
  • Take blood-thinning medicines your provider prescribes.
  • Do not smoke. Smoking increases the risk for blood clots. Talk to your provider if you need help quitting.
What are the latest Deep Vein Thrombosis Clinical Trials?
The DISTINCT Trial: inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT: a National, Multicenter, Randomized, Multi-arm, Open-label Trial.

Summary: After hip or knee replacement all patients receive a standardized treatment with blood thinners, this medication is called thrombosis prophylaxis. However, despite this standard treatment some individuals still develop venous thrombosis (VTE), while others experience bleeding. This indicates that not all patients have the same VTE risk following surgery. Individualizing the amount of thrombosis pr...

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NEI Intramural Biorepository for Retinal Diseases

Background: \- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye disease. Studying genes, cells, and tissues may help them understand why some people get eye problems and others do not, or why some pe...

Who are the sources who wrote this article ?

Published Date: April 01, 2025
Published By: Linda J. Vorvick, MD, Clinical Professor Emeritus, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Aziz MU, Zahid M, Weber TM, Robbin ML. Peripheral veins. In: Rumack CM, Levine D, eds. Diagnostic Ultrasound. 6th ed. Philadelphia, PA: Elsevier; 2024:chap 26.

Chan NC, Weitz JI. Venous thromboembolism. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 140.

Kabrhel C. Pulmonary embolism and deep vein thrombosis. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 74.

Stevens SM, Woller SC, Kreuziger LB, et al. Antithrombotic therapy for VTE disease: second update of the CHEST guideline and expert panel report. Chest. 2021;160(6):e545-e608. PMID: 34352278 pubmed.ncbi.nlm.nih.gov/34352278/.

Weitz JI, Eikelboom JW. Venous thrombosis and embolism. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 68.