Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed computerized cognitive tests. These tests are designed to permit the early detection of individuals at risk of age-related cognitive decline.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 89
Healthy Volunteers: t
View:
• Must be able to use computer mouse and touch screen
• Must speak English as a primary language
• Must speak Spanish as a primary language (for Latino participants completing our Spanish translation)
Locations
United States
California
Neurobehavioral Systems, Inc.
RECRUITING
Berkeley
Contact Information
Primary
Kathleen Hall, PhD
clinical_trial_coordinator@neurobs.com
510-214-3176
Backup
David Woods
drdlwoods@neurobs.com
5105279231
Time Frame
Start Date: 2021-05-05
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 2000
Treatments
Experimental: Older participant group
We will evaluate the performance of healthy older participants (N = 300, age range 60 to 89 years) for three days at enrollment and then at 6-month intervals for three years thereafter. The goal is to characterize changes in performance to aging and task experience in a group of older subjects.
Experimental: CCAB vs. manual test group
We will compare the performance of normal participants (N = 100, age range 18 to 89) on computerized and manually administered cognitive tasks.
Experimental: Test-Retest Reliability group
We will gather normative data from participants across the age range (N = 100, ages 18 to 89) for three days at enrollment, to better characterize test-retest reliability scores on Day 1 tasks.
Experimental: Health Disparities group
We will evaluate the performance of healthy older participants (N = 1200, age range 50 to 89 years) for three days at enrollment and then at 6-month intervals for three years thereafter. In the aim of better understanding health disparities in cognitive testing, this group will be divided into four cohorts: 300 African American participants; 300 Asian American participants; 300 Latino English-speaking participants; and 300 Latino Spanish-speaking participants, who will complete a Spanish translation of our computerized cognitive tests.
Related Therapeutic Areas
Sponsors
Leads: Neurobehavioral Systems, Inc.
Collaborators: National Institutes of Health (NIH)