Reducing African Americans' Alzheimer's Disease Risk Through Exercise-Mild Cognitive Impairment Cohort

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The RAATE-MCI proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group. RAATE-MCI is a 52-week randomized controlled trial. 144 African American adults aged 60 and older will be recruited.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:

• are African American (self-identify)

• are 60 and older

• are physically capable of exercise

• are willing to accept randomization

• are willing to attend group sessions

• plan to live in the study area over the next 13 months and capable of traveling to designated study facility for clinic visits and intervention sessions for the next year

• are free of conditions (e.g. uncontrolled asthma, severe sickle cell disease, etc.) that would make regular exercise unsafe as deemed by the medical investigator

• have not engaged in regular physical activity

• have a Short Physical Performance Battery ≥4

⁃ physically capable of exercise

⁃ are unable to utilize devices and/or applications as required for study participation

⁃ willing to attend group sessions

⁃ willing to allow researchers to use data for research purposes after study participation is completed

⁃ meet criteria for MCI as defined by the NIA-AA research framework a. cognitive performance below normal range (score \< 1.5 SDs below the mean on NIH Toolbox scores for their age and sex on at least one of the subtests)

Locations
United States
Louisiana
Pennington Biomedical Research
RECRUITING
Baton Rouge
Contact Information
Primary
Callie Hebert, MS
callie.hebert@pbrc.edu
225-763-2362
Time Frame
Start Date: 2021-06-01
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 144
Treatments
Experimental: Physical Activity
150 minutes of physical activity weekly
Experimental: Successful Aging
Low intensity activity program and a healthy aging educational component
Authors
Robert Newton
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Aging (NIA)
Leads: Pennington Biomedical Research Center

This content was sourced from clinicaltrials.gov