Development of a Personalized Intervention to Motivate Health Behavior Change in Midlife Adults at Risk for Alzheimer's Disease

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Modifying health behaviors like physical activity level, diet, stress, and mental activity level can lower risk for Alzheimer's disease, but many middle-aged and older adults find it difficult to sustain health behavior changes over the long term. This project will develop a new intervention that educates people about Alzheimer's disease risk factors and helps them understand how their personal health beliefs may prevent them from making long-lasting lifestyle changes. The goal is to help people sustain health behavior changes to prevent or delay the onset of Alzheimer's disease and related dementias.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 69
Healthy Volunteers: t
View:

• age 45-69 years

• normal cognition (Minnesota Cognitive Acuity Scale \> 52)

• English language fluency

• at least two of the following: i) BMI \> 24.9; ii) systolic blood pressure \> 125 mmHg; iii) LDL cholesterol \> 115 mg/dL; iv) HbA1C \> 6.0%; v) at least one APOE ε4 allele; vi) first-degree relative with AD.

Locations
United States
Rhode Island
Rhode Island Hospital
RECRUITING
Providence
Contact Information
Primary
Laura Korthauer, PhD
laura_korthauer@brown.edu
4014444500
Time Frame
Start Date: 2024-03-01
Estimated Completion Date: 2025-02-01
Participants
Target number of participants: 40
Treatments
Active_comparator: Healthy Living Education
The basic healthy living education intervention is a 24-session program (two sessions/week for 12 weeks) designed to educate participants about major modifiable risk factors for Alzheimer's disease. The first session each week is didactic, intended to increase knowledge about each Alzheimer's disease risk factor. The second session involves repetition and practice of didactic material as well as strategizing cues to action
Experimental: Enhanced Healthy Living Education
The enhanced healthy living education intervention will include the same didactic content as the basic HLE course for the first session each week. The second session will focus on personal health beliefs and how they affect specific health behaviors. This may include discussing perceived benefits, troubleshooting barriers to action, making specific action plans, and implementing natural reward systems to bolster self-efficacy.
Related Therapeutic Areas
Sponsors
Leads: Rhode Island Hospital

This content was sourced from clinicaltrials.gov