Low-Cost Virtual Therapeutics and Digital Biomarkers for the Early Assessment and Personalized Treatment of Mild Cognitive Impairment

Status: Recruiting
Location: See location...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Mild Cognitive Impairment (MCI) is a term used to describe the transitional stage that occurs between normal aging and the onset of dementia. Spatial disorientation is often considered a significant indicator for diagnosing dementia. Numerous studies have documented deficits in both the allocentric and egocentric spatial frames of reference, as well as difficulties in transitioning between them, in individuals with MCI. Rapid advances in computing technology have enabled researchers to conduct cognitive training and rehabilitation interventions with the assistance of technology. Therefore, the aim of the study is to use virtual therapeutics to train MCI spatial memory.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Healthy Volunteers: f
View:

• a change in cognition recognized by patients or observers (Caregiver/examiner)

• an objective impairment in one or more cognitive domains using traditional neuropsychological tests;

• autonomy or slight dependence on daily life activities;

• absence of diagnosis of dementia

• absence of cognitive impairment measured by the mini-mental state examination;

• aged 65 or over

Locations
Other Locations
Italy
Istituto Auxologico Italiano
RECRUITING
Milan
Contact Information
Primary
Cosimo Tuena
c.tuena@auxologico.it
0261911
Backup
Chiara Stramba-Badiale
c.strambabadiale@auxologico.it
Time Frame
Start Date: 2023-10-17
Estimated Completion Date: 2026-07
Participants
Target number of participants: 36
Treatments
Active_comparator: TAU
the treatment as usual (TAU; i.e., visuospatial paper and pencil stimulation) will consist of paper and pencil exercises used in clinical routine of 8 sessions of 30/40 minutes 3 times a week.
Experimental: VR non-embodied
the non-embodied spatial training will consist of egocentric and allocentric spatial memory training with passive navigation of 8 sessions of 30/40 minutes 3 times a week.
Experimental: VR embodied
the embodied spatial training will consist of egocentric and allocentric spatial memory training with active navigation of 8 sessions of 30/40 minutes 3 times a week.
Related Therapeutic Areas
Sponsors
Leads: Istituto Auxologico Italiano
Collaborators: University of Turin, Italy, Istituto Superiore di Sanità

This content was sourced from clinicaltrials.gov