Effects of Multidomain Intervention on Cognitive Function in Community-dwelling Elderly

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aging population has contributed to an increase in cognitive decline. To mitigate the rise in the dementia population, it is crucial to prevent cognitive decline in older adults with normal functioning, subjective cognitive decline (SCD), and mild cognitive impairment (MCI). Maintaining cognitive abilities as early as possible is essential for improved overall health and quality of life. Healthcare for the elderly should focus on strengthening health promotion related to aging factors, such as cognitive function, mobility, nutrition, chronic disease management, oral health, fall prevention, transportation safety, psychosocial factors, and sleep. Additionally, as the etiology of dementia is multifactorial, numerous studies have been devoted to multidomain intervention, targeting multiple factors and domains in combination to enhance functions. The cumulative or synergistic effects of multidomain have garnered significant attention for their effectiveness in improving or maintaining the function of the elderly. Therefore, this study aims to evaluate the effects of multidomain intervention, including combined physical and cognitive training, nutrition, chronic disease management, oral health, fall prevention, transportation safety, psychosocial factors, and sleep, on cognitive function in community-dwelling older adults.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: t
View:

• Age ≥ 60 years old

• Mini-Mental State Examination (MMSE) score \> 20 (Folstein et al., 1975), able to follow instructions and participate in activities

• With self-reported or caregiver-reported memory or cognitive-related problems

• No diagnosis of any type of dementia

Locations
Other Locations
Taiwan
Chang Gung Memotial Hospital
RECRUITING
Taoyuan District
Contact Information
Primary
Ching-yi Wu, ScD
cywu@mail.cgu.edu.tw
#886-3-2118800
Time Frame
Start Date: 2023-07-31
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 120
Treatments
Experimental: intervention grou[
Behavioral: multidomain intervention Dosage: a 2-hour session once a week for 12 weeks. Each multidomain intervention session includes 1 hour of combined physical (balance, strength and aerobic exercises) and cognitive (attention, memory, calculation, visual-spatial ability, processing speed and executive function) training and 1 hour of risk factor prevention and management strategies (nutrition, chronic disease management, oral health, fall prevention and transportation safety, psychosocial factors and sleep).
No_intervention: control group
Waiting for 12 weeks (waiting-list control group)
Related Therapeutic Areas
Sponsors
Leads: Chang Gung Memorial Hospital

This content was sourced from clinicaltrials.gov