Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects. The main questions it aims to answer are: 1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects. 2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up. Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including : * A semi-structured interview to check the participants eligibility and gather demographic data. * Neuropsychological tests and questionnaires will then be administered. * A relative of the study participant will help complete questionnaires.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: t
View:

• 60 years and older

• French-speaking and volunteering for the study

• Living at home with a relative

⁃ Alzheimer's disease inclusion criteria:

• Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)

• MMSE greater than or equal to 20

• Diagnosis of Idiopathic Parkinson's disease

• MMSE greater than or equal to 20

Locations
Other Locations
France
CHU de Montpellier - CEPMo
RECRUITING
Montpellier
CHU de Montpellier - CMRR
NOT_YET_RECRUITING
Montpellier
Montpellier Seniors' Association
NOT_YET_RECRUITING
Montpellier
Contact Information
Primary
Mikaël Genguelou, PhD
mikael.genguelou@univ-montp3.fr
06.04.45.37.94.
Backup
KARIM BENNYS, MD
k-bennys@chu-montpellier.fr
04.67.33.72.32
Time Frame
Start Date: 2025-02-04
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 120
Treatments
Experimental: patient with early-onset Alzheimer's disease (AD)
patients followed up at the Centre Mémoire de Ressources et de Recherche (CMRR) of Montpellier, over 60 with Alzheimer's disease who have cognitive impairment based on an MMSE (Mini Mental State Examination) ≥ 20 and live at home with a relative
Active_comparator: patients with parkinson's disease (PD)
patients followed up at the Center Expert Parkinson of Montpellier (CEPMo), over 60 with Parkinson's disease who have cognitive impairment based on an MMSE (Mini Mental State Examination) ≥ 20 and live at home with a relative
Active_comparator: Healthy control
Subjects aged over 60, with no known neurodegenerative disease, living at home with a relative in the Hérault département.
Sponsors
Leads: University Hospital, Montpellier
Collaborators: Laboratoire EPSYLON

This content was sourced from clinicaltrials.gov