Memory for Music: Effects of Individual Intensive Musical Training Based on Singing in Non-musicians With Alzheimer's Disease

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Behavioral, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This project, called Memory for Music, focuses on the increasing number of people worldwide living with dementia, especially Alzheimer's disease (AD). AD typically starts with memory problems and eventually affects daily activities. Active music interventions, especially singing, have shown positive effects on mood, behavior, and quality of life for people with dementia, but their impact on cognition is not well understood. The project aims to address this gap by studying the effects of learning new songs on cognitive, behavioral, and brain functioning. The study will involve home-dwelling adults aged 65 or older with AD from Argentina, Austria, and Norway. Participants will undergo 5 months of intensive musical training (twice a week) and 5 months of minimal training (once a month) in a random order, with a 2-month break in between. The interventions include learning new songs with a personal music teacher. General cognition will be measured using the Alzheimer's Disease Assessment Scale - Cognitive (ADAS-cog), and memory for music will be assessed through various methods, including behavioral tasks and brain responses (EEG). Mood will also be evaluated in each session. The goal is to include 113 participants to ensure reliable detection of meaningful effects. The study will explore how mood and memory for music contribute to changes in cognitive abilities, and whether these effects vary based on factors such as sex, age, AD stage, or previous musical training and general education. The project emphasizes collaboration between researchers, service providers, and users to ensure the study's relevance and applicability.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 65
Healthy Volunteers: f
View:

• Diagnosis of Alzheimer's disease

• Home-dwelling

• Non-musician

Locations
Other Locations
Argentina
Universidad de Ciencias Empresariales y Sociales
NOT_YET_RECRUITING
Buenos Aires
Austria
University of Vienna
NOT_YET_RECRUITING
Vienna
Norway
Haraldsplass Diakonale Sykehus
NOT_YET_RECRUITING
Bergen
University of Bergen
RECRUITING
Bergen
Kinn municipality
NOT_YET_RECRUITING
Florø
Oslo municipality
RECRUITING
Oslo
Contact Information
Primary
Elias Langeland
elil@norceresearch.no
0047 90628887
Backup
Christian Gold
chgo@norceresearch.no
0047 97501757
Time Frame
Start Date: 2024-12-01
Estimated Completion Date: 2027-10-01
Participants
Target number of participants: 113
Treatments
Experimental: Intensive followed by minimal music training
Music training conducted by a trained instructor (music therapist or music educator):~2 sessions per week for 5 months (intensive); no intervention for 2 months (washout period);~1 session per month for 5 months (minimal).
Experimental: Minimal followed by intensive music training
Music training conducted by a trained instructor (music therapist or music educator):~1. session per month for 5 months (minimal); no intervention for 2 months (washout period);~2. sessions per week for 5 months (intensive).
Related Therapeutic Areas
Sponsors
Collaborators: University of Bergen, University of Vienna, Universidad de Ciencias Empresariales y Sociales, Buenos Aires, Argentina, Oslo Municipality, Oslo Dementia Association, Kinn Municipality, Norway, Norwegian Association for Music Therapy, Universidad Nacional de Entre Rios
Leads: NORCE Norwegian Research Centre AS

This content was sourced from clinicaltrials.gov

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