Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
A central goal of this data repository is to collect data from a large population of subjects with a variety of renal disease states. Cohorts will include subjects with diabetes, inflammatory/autoimmune and transplant related renal conditions. Additionally, the repository will have the capacity to store biospecimens and electronic data in control subjects without established renal disease. This initiative will provide an opportunity to compare data from various disease states and controls with the objective of determining clinical and biological factors that predict disease progression, response to therapy and identify discriminating noninvasive clinical and biological features that predict renal biopsy findings.
⁃ All Groups:
• Males or females
• 18 years of age and older
• Willing and able to provide informed consent
⁃ Native Biopsy Tissue Group:
⁃ \- Require an initial kidney biopsy for medical necessity
⁃ Native Kidney, Non-tissue Group:
• Previously had a kidney biopsy and the tissue is not stored in this biorepository; or
• Have diabetes and kidney disease and have not had a kidney biopsy
⁃ Allograft Tissue Group:
⁃ \- Have undergone a renal transplant and require a transplant biopsy for either surveillance or for-cause indications.