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Last Updated: 10/31/2025
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Found 297 publications
Suspected capecitabine-induced fatal toxicity in the context of a new DPYD variant.
Journal: BMJ case reports
Published: August 31, 2025
Reducing Fluorouracil Doses in Patients With Partial Dihydropyrimidine Dehydrogenase Deficiency Is a Treatment Safety Strategy, Not a Panacea of Precision Dosing.
Journal: JCO precision oncology
Published: July 10, 2025
A Lack of Complete Linkage Disequilibrium Between c.1236G>A and c.1129-5923C>G HapB3 Variants of DPYD: A Call to Revise European Pharmacogenetic Guidelines.
Journal: International journal of molecular sciences
Published: July 05, 2025
Clinical Implications of a Large-Scale Voluntary Preemptive DPYD Testing Program for Patients Planned for a Systemic Fluoropyrimidine: Preliminary Results.
Journal: JCO oncology practice
Published: June 12, 2025
Phenotyping and genotyping for the dihydropyrimidine dehydrogenase test in Italy: a precise diagnostic strategy to detect rare variants and improve drug administration.
Journal: Clinical biochemistry
Published: May 17, 2025
A thymine-challenge test to prospectively evaluate dihydropyrimidine dehydrogenase activity for risk of severe 5-fluorouracil-induced gastrointestinal toxicity.
Journal: Cancer chemotherapy and pharmacology
Published: April 30, 2025
Bowel Ischemia From Suspected Non-occlusive Mesenteric Ischemia: A Case Report.
Journal: Cureus
Published: April 29, 2025
Application of dihydropyrimidine dehydrogenase deficiency testing for the prevention of fluoropyrimidine toxicity: a real-world experience in a Southern Italy cancer center.
Journal: Journal of chemotherapy (Florence, Italy)
Published: April 18, 2025
Securing Fluoropyrimidine-based chemotherapy: comparison of three methods of screening for dihydropyrimidine dehydrogenase deficiency.
Journal: European review for medical and pharmacological sciences
Published: April 02, 2025
Trifluridine- and tipiracil-induced DPD inhibition mimicking DPD deficiency: a case report.
Journal: Frontiers in oncology
Published: March 10, 2025
Pharmacogenetic Testing for DPD Deficiency: Four and a Half Years' Experience in a Large German Laboratory.
Journal: Deutsches Arzteblatt international
Published: February 10, 2025
Optimizing fluoropyrimidine therapy: Real-world impact of DPYD genotype-based dosing on severe toxicity rates.
Journal: British journal of clinical pharmacology
Published: January 15, 2025
Last Updated: 10/31/2025