Discoid Lupus Erythematosus (DLE) Overview

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Learn About Discoid Lupus Erythematosus (DLE)

What is the definition of Discoid Lupus Erythematosus (DLE)?
Discoid lupus erythematosus is a type of cutaneous lupus erythematosus, or inflammatory skin disorder, that causes circular skin lesions on the scalp or face.
What are the symptoms of Discoid Lupus Erythematosus (DLE)?
Symptoms of discoid lupus erythematosus include circular, scaly, thick, or red lesions about the size of coin, usually on the scalp and face. These lesions can also appear on other parts of the body and inside the mouth. The lesions from discoid lupus erythematosus can also cause permanent hair loss on the scalp, scarring, and loss of skin pigmentation.
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What are the current treatments for Discoid Lupus Erythematosus (DLE)?
Treatment for discoid lupus erythematosus depends on the severity. Treatments for discoid lupus erythematosus include medications such as steroid ointments, dapsone, methotrexate, mycophenolate mofetil, azathioprine, intravenous immunoglobulin, cyclophosphamide, cyclosporine, hydroxychloroquine, chloroquine, quinacrine, tacrolimus, pimecrolimus cream, intralesional triamcinolone acetonide, topical retinoids, vitamin A analogs, thalidomide, and lenalidomide. Individuals with discoid lupus erythematosus should also avoid sun exposure, use sunscreen, and stop smoking.
Who are the top Discoid Lupus Erythematosus (DLE) Local Doctors?
Dr. Misty T. Sharp
Dermatology
Dr. Misty T. Sharp
Dermatology

Westmoreland Dermatology & Surgery Center PA

2110 5th St N, 
Columbus, MS 
 (30.1 mi)
662-243-2435
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Misty Sharp is a Dermatologist in Columbus, Mississippi. Dr. Sharp and is rated as an Experienced provider by MediFind in the treatment of Discoid Lupus Erythematosus (DLE). Her top areas of expertise are Atopic Dermatitis, Squamous Cell Skin Carcinoma, Actinic Keratosis, and Lichen Planus. Dr. Sharp is currently accepting new patients.

Dr. Richard E. Jones
Rheumatology
Dr. Richard E. Jones
Rheumatology

Wv Medical Services PC

4280 Watermelon Rd, Suite 112, 
Northport, AL 
 (31.5 mi)
205-750-0030
Languages Spoken:
English, Spanish
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Accepting New Patients

Richard Jones is a Rheumatologist in Northport, Alabama. Dr. Jones and is rated as an Advanced provider by MediFind in the treatment of Discoid Lupus Erythematosus (DLE). His top areas of expertise are Rheumatoid Arthritis (RA), Osteoporosis, Postmenopausal Osteoporosis, and Polymyositis. Dr. Jones is currently accepting new patients.

 
 
 
 
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Nancy Ashford, NP
Nurse Practitioner
Nancy Ashford, NP
Nurse Practitioner

The Columbus Orthopaedic Clinic, P.A.

670 Leigh Dr, 
Columbus, MS 
 (26.5 mi)
662-328-1012
Experience:
9+ years
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Nancy Ashford is a Nurse Practitioner in Columbus, Mississippi. Ashford has been practicing medicine for over 9 years and is rated as an Experienced provider by MediFind in the treatment of Discoid Lupus Erythematosus (DLE). Her top areas of expertise are Opioid Induced Constipation, Muscle Spasms, Phantom Limb Pain, and Sacroiliac Joint Disease. Ashford is currently accepting new patients.

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What are the latest Discoid Lupus Erythematosus (DLE) Clinical Trials?
A Phase 2, Single-Blind, Intraindividual Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects with Discoid Lupus Erythematosus
A Phase 2, Single-Blind, Intraindividual Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects with Discoid Lupus Erythematosus
Enrollment Status: Recruiting
Publish Date: September 19, 2024
Intervention Type: Drug, Procedure
Study Phase: Phase 2

Summary: This study is a single-blind, intraindividual study to evaluate the efficacy of ruxolitinib 1.5 % cream in adult subjects with discoid lupus erythematosus.

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A Phase II, Double-blind, Dose-Ranging, Parallel, Long-term Extension Study to Evaluate the Safety and Efficacy of Enpatoran in Participants With Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus and/or Systemic Lupus Erythematosus Having Completed the WILLOW (MS200569_0003) Study Treatment (WILLOW LTE)
A Phase II, Double-blind, Dose-Ranging, Parallel, Long-term Extension Study to Evaluate the Safety and Efficacy of Enpatoran in Participants With Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus and/or Systemic Lupus Erythematosus Having Completed the WILLOW (MS200569_0003) Study Treatment (WILLOW LTE)
Enrollment Status: Recruiting
Publish Date: August 09, 2024
Intervention Type: Drug
Study Phase: Phase 2

Summary: The purpose of the study is to evaluate the long term safety and efficacy of orally administered M5049 in participants with subacute cutaneous lupus erythematosus (SCLE), discoid lupus erythematosus (DLE) and/or systemic lupus erythematosus (SLE) who have completed the 24 week treatment period of Willow study (MS200569_0003 \[NCT05162586\]).

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