Dopa-Responsive DystoniaSymptoms, Doctors, Treatments, Advances & More
Learn About Dopa-Responsive Dystonia
View Main Condition: Movement Disorders
Dopa-responsive dystonia is a disorder that involves involuntary muscle contractions, tremors, and other uncontrolled movements (dystonia). The features of this condition range from mild to severe. This form of dystonia is called dopa-responsive dystonia because the signs and symptoms typically improve with sustained use of a medication known as L-Dopa.
Mutations in the GCH1 gene are the most common cause of dopa-responsive dystonia. Less often, mutations in the TH or SPR gene cause this condition.
Dopa-responsive dystonia is estimated to affect 1 per million people worldwide. However, the disorder is likely underdiagnosed because the condition may not be identified in people with mild symptoms, or it may be misdiagnosed in people who have symptoms similar to other movement disorders.
When dopa-responsive dystonia is caused by mutations in the GCH1 gene, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In some cases, an affected person inherits the mutation from one affected parent. Other cases result from new mutations in the gene and occur in people with no history of the disorder in their family.
Atrium Health Neurology Specialty Care, A Facility Of Carolinas Medical Center
Danielle Doggett is a Neurologist practicing medicine in Charlotte, North Carolina. Dr. Doggett is rated as an Advanced provider by MediFind in the treatment of Dopa-Responsive Dystonia. She is also highly rated in 19 other conditions, according to our data. Her clinical expertise encompasses Parkinson's Disease, Movement Disorders, Essential Tremor, Drug Induced Dyskinesia, and Deep Brain Stimulation. Dr. Doggett is board certified in American Board Of Psychiatry And Neurology. Dr. Doggett is currently accepting new patients.
Aurora Neuroscience Innovation
Taylor Finseth is a Neurologist practicing medicine in Milwaukee, Wisconsin. Dr. Finseth is rated as an Advanced provider by MediFind in the treatment of Dopa-Responsive Dystonia. He is also highly rated in 24 other conditions, according to our data. His clinical expertise encompasses Camptocormism, Parkinson's Disease, Movement Disorders, and Conversion Disorder. Dr. Finseth is board certified in American Board Of Psychiatry & Neurology.
Anne Weissbach practices practicing medicine in Luebeck, Germany. Ms. Weissbach is rated as an Elite expert by MediFind in the treatment of Dopa-Responsive Dystonia. She is also highly rated in 10 other conditions, according to our data. Her clinical expertise encompasses Dopa-Responsive Dystonia, Myoclonus-Dystonia, Focal Dystonia, Movement Disorders, and Deep Brain Stimulation.
Published Date: May 01, 2012
Published By: National Institutes of Health