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Generic Name

CycloSPORINE

Brand Names
CEQUA, Sandimmune, Restasis MultiDose, Verkazia, Neoral, Restasis, Gengraf, VEVYE
FDA approval date: November 14, 1983
Classification: Calcineurin Inhibitor Immunosuppressant
Form: Injection, Emulsion, Capsule, Solution

What is CEQUA (CycloSPORINE)?

Kidney, Liver, and Heart Transplantation Cyclosporine capsules is indicated for the prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants. Cyclosporine capsules has been used in combination with azathioprine and corticosteroids. Rheumatoid Arthritis Cyclosporine capsules is indicated for the treatment of patients with severe active, rheumatoid arthritis where the disease has not adequately responded to methotrexate. Cyclosporine capsules can be used in combination with methotrexate in rheumatoid arthritis patients who do not respond adequately to methotrexate alone. Psoriasis Cyclosporine capsules is indicated for the treatment of adult, nonimmunocompromised patients with severe , recalcitrant, plaque psoriasis who have failed to respond to at least one systemic therapy or in patients for whom other systemic therapies are contraindicated or cannot be tolerated. While rebound rarely occurs, most patients will experience relapse with cyclosporine capsules as with other therapies upon cessation of treatment.
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Phase II Study of Horse Anti-Thymocyte Globulin (hATG), Cyclosporine, Methylprednisolone, and GCSF (Filgrastim or Pegfilgrastim) in Patients With Aplastic Anemia (AA), or Low/Int-1 Risk Myelodysplastic Syndrome (MDS)

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Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Background: * Membranous nephropathy is associated with damage to the walls of the glomeruli, the small blood vessels in the kidneys that filter waste products from the blood. This damage causes leakage of blood proteins into the urine and is associated with low blood protein levels, high blood cholesterol values, and swelling of the legs. These problems can decrease or go away without treatment in about 25 p...

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