The Potential Relationship Between the Palmaris Longus Muscle Prevalence and Dupuytren Disease: a Comparative Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Dupuytren disease is a medical condition characterized by the painless formation of nodules in the palm of the hand. Cords are formed on the palmar fascia, a connective tissue sheet in the palm of the hand. This fascia is seen as the vestigial remnant of the palmaris longus tendon. The PLM attaches to the fascia palmaris. A muscle that not everyone has and can therefore be clearly missed. This raises the question of whether the presence of the musculus palmaris longus has any association with the development, recurrence and/or progression of DD and contractures. To investigate a potential predisposition, this study intend to assess the prevalence of the PLM in a group of individuals affected by DD and compare it with a control group (age matched, no signs of DD) without the condition.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: t
View:

• The participant or his/her legally authorized representative voluntary signed the informed consent prior to the first assessment.

• 50 years of age or higher.

• Has Dupuytren disease (primary or recurrent). (Only applicable for participants of DD group)

• Has no medical conditions affecting the function of the hand (musculoskeletal pathology, vascular or neurological conditions such as CRPS, rheumatoid arthritis and paralysis). (Only applicable for participants of control group)

Locations
Other Locations
Belgium
Universitaire Ziekenhuizen KU Leuven
RECRUITING
Leuven
Contact Information
Primary
Ilse Degreef, Prof. Dr.
ilse.degreef@uzleuven.be
+32 16 33 88 43
Backup
Anna Tarasiuk
orthopedie.research@uzleuven.be
+32 16 33 88 18
Time Frame
Start Date: 2024-02-16
Estimated Completion Date: 2025-06-01
Participants
Target number of participants: 240
Treatments
Experimental: Patients with Dupuytren disease
120 individuals diagnosed with Dupuytren disease (primary or recurrent).
Experimental: Healthy controls
120 participants with no other medical conditions affecting the function of the hand (musculoskeletal pathology, vascular or neurological conditions such as CRPS, rheumatoid arthritis and paralysis).
Related Therapeutic Areas
Sponsors
Leads: Universitaire Ziekenhuizen KU Leuven

This content was sourced from clinicaltrials.gov