Learn About Enlarged Liver

What is the definition of Enlarged Liver?

Enlarged liver refers to swelling of the liver beyond its normal size. Hepatomegaly is another word to describe this problem.

If both the liver and spleen are enlarged, it is called hepatosplenomegaly.

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What are the alternative names for Enlarged Liver?

Hepatosplenomegaly; Enlarged liver; Liver enlargement

What is some background information about Enlarged Liver?

The lower edge of the liver normally comes just to the lower edge of the ribs on the right side. The edge of the liver is normally thin and firm. It cannot be felt with the fingertips below the edge of the ribs, except when you take a deep breath. It may be enlarged if a health care provider can feel it in this area.

What are the causes of Enlarged Liver?

The liver is involved in many of the body's functions. It is affected by many conditions that can cause hepatomegaly, including:

  • Alcohol use (especially alcohol abuse)
  • Cancer metastases (spread of cancer to the liver)
  • Congestive heart failure
  • Glycogen storage disease
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Hepatocellular carcinoma
  • Hereditary fructose intolerance
  • Infectious mononucleosis
  • Leukemia
  • Niemann-Pick disease
  • Primary biliary cholangitis
  • Reye syndrome
  • Sarcoidosis
  • Sclerosing cholangitis
  • Portal vein thrombosis
  • Steatosis (fat in the liver from metabolic problems such as diabetes, obesity, and high triglycerides, also called nonalcoholic steatohepatitis, or NASH)
When should I contact a medical professional for Enlarged Liver?

This condition is most often detected by a provider. You may not be aware of the liver or spleen swelling.

What should I expect during a doctor appointment?

The provider will examine you and ask questions such as:

  • Did you notice fullness or a lump in the abdomen?
  • What other symptoms do you have?
  • Is there any abdominal pain?
  • Is there any yellowing of the skin (jaundice)?
  • Is there any vomiting?
  • Is there any unusual-colored or pale-colored stools?
  • Has your urine appeared to be darker than usual (brownish)?
  • Have you had a fever?
  • What medicines are you taking including over-the-counter and herbal medicines?
  • How much alcohol do you drink?

Tests to determine the cause of hepatomegaly vary, depending on the suspected cause, but may include:

  • Abdominal x-ray
  • Abdominal ultrasound (may be done to confirm the condition if the provider thinks your liver feels enlarged during a physical exam)
  • CT scan of the abdomen
  • Liver function tests, including blood clotting tests
  • MRI scan of the abdomen
Fatty liver - CT scan
Liver with disproportional fattening - CT scan
Hepatomegaly
Who are the top Enlarged Liver Local Doctors?
Distinguished
Highly rated in
32
conditions
Gastroenterology
Hepatology

Loyola University Health System

Loyola Center For Health At Burr Ridge

6800 N Frontage Rd 
Burr Ridge, IL 60527

Scott Cotler is a Gastroenterologist and a Hepatologist in Burr Ridge, Illinois. Dr. Cotler has been practicing medicine for over 32 years and is rated as a Distinguished doctor by MediFind in the treatment of Enlarged Liver. He is also highly rated in 32 other conditions, according to our data. His top areas of expertise are Hepatitis, Hepatitis C, Ascites, and Cirrhosis. He is licensed to treat patients in Illinois. Dr. Cotler is currently accepting new patients.

Distinguished
Highly rated in
24
conditions
Gastroenterology
Hepatology

Loyola University Health System

Loyola Center For Health At Burr Ridge

6800 N Frontage Rd 
Burr Ridge, IL 60527

Jamie Berkes is a Gastroenterologist and a Hepatologist in Burr Ridge, Illinois. Dr. Berkes has been practicing medicine for over 24 years and is rated as a Distinguished doctor by MediFind in the treatment of Enlarged Liver. He is also highly rated in 24 other conditions, according to our data. His top areas of expertise are Visceromegaly, Alcoholic Cirrhosis, Enlarged Liver, and Cirrhosis. He is licensed to treat patients in Illinois. Dr. Berkes is currently accepting new patients.

 
 
 
 
Learn about our expert tiers
Learn more
Distinguished
Highly rated in
25
conditions
Gastroenterology
Hepatology

Loyola University Health System

Loyola University Medical Center

2160 S 1st Ave 
Maywood, IL 60153

Steven Scaglione is a Gastroenterologist and a Hepatologist in Maywood, Illinois. Dr. Scaglione has been practicing medicine for over 19 years and is rated as a Distinguished doctor by MediFind in the treatment of Enlarged Liver. He is also highly rated in 25 other conditions, according to our data. His top areas of expertise are Visceromegaly, Hepatitis, Cirrhosis, and Hepatitis C. He is licensed to treat patients in Illinois. Dr. Scaglione is currently accepting new patients.

What are the latest Enlarged Liver Clinical Trials?
A Phase 4, Single-arm, Open-label Safety and Efficacy Study of Aldurazyme® (Laronidase) as Enzyme Replacement Therapy in Participants With Mucopolysaccharidosis I (MPS I) in China
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A Phase II Study of Isatuximab (SAR650984) (NSC-795145) for Patients With Previously Treated AL Amyloidosis
What are the Latest Advances for Enlarged Liver?
Long-term efficacy and safety of vestronidase alfa enzyme replacement therapy in pediatric subjects < 5 years with mucopolysaccharidosis VII.
Bacteremic and Nonbacteremic Brucellosis in Children in Turkey.
Tired of the same old research?
Check Latest Advances
Abdominal pain and cirrhosis at diagnosis of hemochromatosis: Analysis of 219 referred probands with HFE p.C282Y homozygosity and a literature review.
Who are the sources who wrote this article ?

Published Date : April 22, 2021
Published By : Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Martin P. Approach to the patient with liver disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 137.

Plevris J, Parks R. The gastrointestinal system. In: Innes JA, Dover AR, Fairhurst K, eds. Macleod's Clinical Examination. 14th ed. Philadelphia, PA: Elsevier; 2018:chap 6.

Squires JE, Balistreri WF. Manifestations of liver disease. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 382.