Fibrostenotic Eosinophilic Esophagitis: Endoscopic, Histologic and Molecular Characterization and Evaluation of Clinical Assessment Tools

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This protocol addresses a central hypothesis that fibrostenotic Eosinophilic Esophagitis (EoE) is characterized by abnormal esophageal structure and compliance compared to non fibrostenotic EoE and that distinctive cellular and molecular profiles predict the fibrostenotic phenotype. This study aims to define and assess the changes that occur in the structure and dynamics of the esophageal wall in pediatric Eosinophilic Esophagitis along with characterizing the histologic and molecular patterns in fibrostenotic EoE.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 18
Healthy Volunteers: f
View:

• Scheduled to undergo a clinical upper endoscopy with biopsy

Locations
United States
Colorado
Children's Hospital Colorado
RECRUITING
Aurora
Contact Information
Primary
Cassandra Burger
cassandra.burger@childrenscolorado.org
720-777-5739
Time Frame
Start Date: 2014-12
Estimated Completion Date: 2024-06
Participants
Target number of participants: 250
Sponsors
Leads: University of Colorado, Denver

This content was sourced from clinicaltrials.gov