Effects of Social Feedback on Intracranial EEG

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to assess the impact of social influence on direct neural recordings in human patients undergoing surgical treatment of epilepsy. 24 patients recruited from the Epilepsy Center at Dartmouth Health Medical Center (DHMC) will undergo electrode implantation throughout the brain to localize epileptogenic zones. Patients will be asked to rate their provider's warmth, competence, and other, similar traits associated with care-competency. They will then complete the picture-induced fear and math portions of the multimodal negative affect task (MNAT) during which iEEG is recorded.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Patients must be between 18-65 years of age.

• Patients must have a diagnosis of refractory epilepsy undergoing intracranial EEG recording for clinical purposes.

• Patients with a legal guardian will be considered for participation if they are interested and, in the judgment of the research team, they are capable of performing the cognitive tasks required of the study. In those instances, the patient and their legal guardian will both participate in the informed consent process, with the legal guardian signing the consent form.

Locations
United States
New Hampshire
Dartmouth Hitchcock Medical Center
RECRUITING
Lebanon
Contact Information
Primary
Tor D Wager, PhD
Tor.D.Wager@Dartmouth.edu
603-646-2196
Time Frame
Start Date: 2023-04-06
Estimated Completion Date: 2028-02-28
Participants
Target number of participants: 24
Treatments
Experimental: Random Order 1: Effects of social feedback on intracranial EEG
Participants experience trials involving presentation of negative affective stimuli and an effort-demanding cognitive task. Trials are preceded by high or low social cues in random order.
Experimental: Random Order 2: Effects of social feedback on intracranial EEG
Participants experience trials involving presentation of negative affective stimuli and an effort-demanding cognitive task. Trials are preceded by high or low social cues in random order.
Related Therapeutic Areas
Sponsors
Leads: Trustees of Dartmouth College

This content was sourced from clinicaltrials.gov