Erythema nodosum is an inflammatory disorder. It involves tender, red bumps (nodules) under the skin.
In about half of cases, the exact cause of erythema nodosum is unknown. The remaining cases are associated with an infection or other systemic disorder.
Some of the more common infections associated with the disorder are:
Erythema nodosum may occur with sensitivity to certain medicines, including:
Sometimes, erythema nodosum may occur during pregnancy.
Other disorders linked to this condition include leukemia, lymphoma, sarcoidosis, rheumatic fever, Behcet disease, and ulcerative colitis.
The condition is more common in women than it is in men.
Erythema nodosum is most common on the front of the shins. It may also occur on other areas of the body such as buttocks, calves, ankles, thighs, and arms.
The lesions begin as flat, firm, hot, red, painful lumps that are about 1 inch (2.5 centimeters) across. Within a few days, they may become purplish in color. Over several weeks, the lumps fade to a brownish, flat patch.
Other symptoms may include:
The underlying infection, drug, or disease should be identified and treated.
Treatment may include:
Stephen Walker is in London, United Kingdom. Walker is rated as an Elite expert by MediFind in the treatment of Erythema Nodosum. He is also highly rated in 7 other conditions, according to our data. His top areas of expertise are Erythema Nodosum, Leprosy, Scabies, and Leishmaniasis.
Tarun Narang is a Gastroenterologist in Charlotte, North Carolina. Dr. Narang has been practicing medicine for over 23 years and is rated as an Elite doctor by MediFind in the treatment of Erythema Nodosum. He is also highly rated in 26 other conditions, according to our data. His top areas of expertise are Erythema Nodosum, Bile Duct Obstruction, Bile Duct Stricture, and Cholestasis. He is licensed to treat patients in New York and North Carolina. Dr. Narang is currently accepting new patients.
Diana Lockwood is in Netherlands. Lockwood is rated as an Elite expert by MediFind in the treatment of Erythema Nodosum. She is also highly rated in 4 other conditions, according to our data. Her top areas of expertise are Leprosy, Erythema Nodosum, Leishmaniasis, and Peripheral Neuropathy.
Erythema nodosum is uncomfortable, but not dangerous in most cases.
Symptoms most often go away within about 6 weeks, but may return.
Contact your provider if you develop symptoms of erythema nodosum.
Published Date : August 14, 2021
Published By : Elika Hoss, MD, Senior Associate Consultant, Mayo Clinic, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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