Learn About Esotropia

What is the definition of Esotropia?
Esotropia is form of eye misalignment (strabismus) in which one or both eyes turn inward. Esotropia can occur at any time in life. There are several types of esotropia that are characterized by its onset, causes, and symptoms, such as accommodative esotropia, non-accommodative esotropia, divergence insufficiency type esotropia, microtropia/monofixation syndrome, sensory esotropia, consecutive esotropia, and other forms of esotropia associated with eye injury, thyroid eye disease, or nerve paralysis.
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What are the symptoms of Esotropia?
Symptoms of esotropia depend on the type and severity of the esotropia but include an inward turning of one or both eyes; lazy eye (amblyopia), in which one eye has decreased vision; and double vision in adults.
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What are the current treatments for Esotropia?
While esotropia in infants under 20 weeks old usually resolves without treatment, in individuals over 4 months old treatment is focused on aligning the eyes, improving vision, relieving double vision, and treating lazy eye (amblyopia). Treatment for esotropia includes the use of glasses, eye patches, eyes exercises, botulinum toxin (Botox), and strabismus surgery.
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What are the latest Esotropia Clinical Trials?
A Pragmatic, Randomized, Non-inferiority Trial Comparing the Effectiveness of Botulinum Toxin-based Treatment With Conventional Strabismus Surgery in Acquired Esotropia.

Summary: The purpose of the study is to evaluate if strabismus can be successfully treated requiring less surgical interventions with a Botox-based treatment regimen compared to a purely surgery based treatment regimen. Experimental arm: Botulinum toxin injection in the horizontal extraocular muscles. Control (active comparator) arm: Strabismus surgery on the horizontal extraocular muscles. No investigatio...

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Validation of a Smartphone-based Intelligent Diagnosis and Measurement for Strabismus

Summary: The current measurement methods of strabismus include the corneal light reflection method, prism alternate covering, etc., which especially rely on the subjective experience of doctors, and there is a large error between different measurers, leading to serious underestimation of strabismus prevalence and insufficient care for strabismus patients. Here, the investigators established and validated a...

What are the Latest Advances for Esotropia?
Long-term follow-up of surgical treatment of thyroid-associated orbitopathy restrictive strabismus.
Non-adjustable surgery for acute acquired comitant esotropia under general anesthesia.
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Botulinum toxin treatment for bielschowsky acquired commitant esotropia in adults.