Exstrophy-Epispadias Complex
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Exstrophy-Epispadias Complex Overview

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Learn About Exstrophy-Epispadias Complex

What is the definition of Exstrophy-Epispadias Complex?
Exstrophy-epispadias complex (EEC) refers to a spectrum of birth defects that includes epispadias, classical bladder exstrophy, and exstrophy of the cloaca and several variants. EEC is characterized by a visible defect of the lower abdominal wall and other problems. In normal development, the cloacal membrane temporarily separates the cloaca (final part of the intestine) into urogenital and anal regions, and it ruptures after fusing with a structure known as the urogenital septum, which is made up of the tissue that will form the abdominal muscles (mesoderm). If the cloacal membrane does not fuse correctly with the urogenital septum, it does not form the mesoderm and, as a result, the abdominal muscles do not form. The exact timing of the rupture determines whether the child is born with isolated epispadias, classic bladder exstrophy, or cloacal exstrophy. Depending on severity, EEC may involve the urinary system, musculoskeletal system, pelvis, pelvic floor, abdominal wall, genitalia, and sometimes the spine and anus. There is no known cause for EEC. The University of Michigan has a webpage about the development of the embryo and its parts, including the formation of the cloaca.
What are the alternative names for Exstrophy-Epispadias Complex?
  • Exstrophy-epispadias complex
  • Exstrophy of the bladder
  • BEEC
  • Bladder exstrophy-epispadias-cloacal extrophy complex
  • EEC
  • Bladder exstrophy
Who are the top Exstrophy-Epispadias Complex Local Doctors?
Elite in Exstrophy-Epispadias Complex
Elite in Exstrophy-Epispadias Complex
Referral may be required

Johns Hopkins Children's Center Pediatric Specialists - Annapolis

820 Bestgate Road, Suite 2D, 
Annapolis, MD 
410-955-6108
Languages Spoken:
English
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Accepting New Patients
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Heather Di Carlo is a Pediatrics provider practicing medicine in Annapolis, Maryland. Dr. Di Carlo is rated as an Elite provider by MediFind in the treatment of Exstrophy-Epispadias Complex. She is also highly rated in 7 other conditions, according to our data. Her clinical expertise encompasses Exstrophy-Epispadias Complex, Cloacal Exstrophy, Epispadias, Bladder Reconstruction, and Osteotomy. Dr. Di Carlo is board certified in American Board Of Urology. Dr. Di Carlo is currently accepting new patients.

Elite in Exstrophy-Epispadias Complex
Elite in Exstrophy-Epispadias Complex
Referral may be required

Johns Hopkins Children's Center

1800 Orleans St, 
Baltimore, MD 
410-955-4494
Experience:
10+ years
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Mahir Maruf is a Urologist practicing medicine in Baltimore, Maryland. He has been practicing medicine for over 10 years. Dr. Maruf is rated as an Elite provider by MediFind in the treatment of Exstrophy-Epispadias Complex. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Exstrophy of the Bladder, Cloacal Exstrophy, Exstrophy-Epispadias Complex, Bladder Reconstruction, and Osteotomy. Dr. Maruf is currently accepting new patients.

 
 
 
 
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Distinguished in Exstrophy-Epispadias Complex
Distinguished in Exstrophy-Epispadias Complex
Referral may be required
675 N St Clair St Ste 20-150, Galter Pavilion, 
Chicago, IL 
312-695-8146
Languages Spoken:
English
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Accepting New Patients
Offers Telehealth

Diana Bowen is a Urologist practicing medicine in Chicago, Illinois. Dr. Bowen is rated as a Distinguished provider by MediFind in the treatment of Exstrophy-Epispadias Complex. She is also highly rated in 15 other conditions, according to our data. Her clinical expertise encompasses Neurogenic Bladder, Myelomeningocele, Exstrophy of the Bladder, Orchiectomy, and Lithotripsy. Dr. Bowen is board certified in American Board Of Urology - Pediatric Urology (Certified). Dr. Bowen is currently accepting new patients.

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What are the latest Exstrophy-Epispadias Complex Clinical Trials?
PROSPECTIVE STUDY EVALUATING THE SAFETY AND EFFECTIVENESS OF ADJUSTABLE CONTINENCE THERAPY (ACT) BALLOONS FOR THE MANAGEMENT OF URINARY INCONTINENCE IN CHILDREN WITH BLADDER EXSTROPHY OR INCONTINENT EPISPADIAS
PROSPECTIVE STUDY EVALUATING THE SAFETY AND EFFECTIVENESS OF ADJUSTABLE CONTINENCE THERAPY (ACT) BALLOONS FOR THE MANAGEMENT OF URINARY INCONTINENCE IN CHILDREN WITH BLADDER EXSTROPHY OR INCONTINENT EPISPADIAS
Enrollment Status: Recruiting
Publish Date: June 23, 2021
Intervention Type: Device
Study Phase: Not Applicable

Summary: The purpose of this study is to evaluate the effectiveness and safety of a minimally invasive surgical procedure with ACT (Adjustable Continence Therapy) balloons implantation for the treatment of urinary incontinence in children with bladder exstrophy or isolated epispadias. The ACT therapy consists of two small adjustable silicone balloons connected with a tubing to a port, surgically placed aro...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center