A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
The purpose of this study is to determine the efficacy and safety of a personalised surveillance and intervention protocol for patients with familial adenomatous polyposis (FAP) that have undergone (procto)colectomy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Diagnosis of FAP, at least one of following: genetic diagnosis (proven APC germline mutation) and/or clinical diagnosis (\>100 colorectal adenomas in combination with a positive family history of FAP)
• Have undergone prophylactic (procto)colectomy with IRA/ISA or IPAA
• Age 18 years or older
Locations
United States
Texas
MD Anderson
RECRUITING
Houston
Other Locations
Netherlands
Academic Medical Centre
RECRUITING
Amsterdam
Time Frame
Start Date: 2021-11-24
Estimated Completion Date: 2026-11
Participants
Target number of participants: 1000
Treatments
Personalized surveillance and intervention protocol
Related Therapeutic Areas
Sponsors
Collaborators: Hospital Clinic of Barcelona, The Netherlands Cancer Institute, Maria Sklodowska-Curie National Research Institute of Oncology, Hospital General Universitario de Alicante, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University Hospital, Bonn, Radboud University Medical Center, St Mark's Hospital Foundation, M.D. Anderson Cancer Center, Leiden University Medical Center, Hvidovre University Hospital
Leads: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)