Learn About Familial Colorectal Cancer

What is the definition of Familial Colorectal Cancer?
Familial colon cancer is a cluster of colon cancer within a family. Most cases of colon cancer occur sporadically in people with little to no family history of the condition. Approximately 3-5% of colon cancer is considered "hereditary" and is thought to be caused by an inherited predisposition to colon cancer that is passed down through a family in an autosomal dominant or autosomal recessive manner. In some of these families, the underlying genetic cause is not known; however, many of these cases are caused by changes (mutations) in the APC, MYH, MLH1, MSH2, MSH6, PMS2, EPCAM, PTEN, STK11, SMAD4, BMPR1A, NTHL1, POLE, and POLD1 genes (which are associated with hereditary cancer syndromes). An additional 10-30% of people diagnosed with colon cancer have a significant family history of the condition but have no identifiable mutation in a gene known to cause a hereditary predisposition to colon cancer. These clusters of colon cancer are likely due to a combination of gene(s) and other shared factors such as environment and lifestyle. High-risk cancer screening and other preventative measures such as prophylactic surgeries are typically recommended in people who have an increased risk for colon cancer based on their personal and/or family histories.
Save information for later
Sign Up
What are the alternative names for Familial Colorectal Cancer?
  • Colorectal cancer, familial
Who are the top Familial Colorectal Cancer Local Doctors?
Elite
Highly rated in
12
conditions
Oncology
Hematology Oncology

Duarte

Duarte, CA 

Marwan Fakih is an Oncologist and a Hematologist Oncology doctor in Duarte, California. Dr. Fakih has been practicing medicine for over 30 years and is rated as an Elite doctor by MediFind in the treatment of Familial Colorectal Cancer. He is also highly rated in 12 other conditions, according to our data. His top areas of expertise are Colorectal Cancer, Familial Colorectal Cancer, Anal Cancer, and Lynch Syndrome. He is board certified in Medical Oncology and licensed to treat patients in Michigan, California, and New York.

Elite
Highly rated in
9
conditions

Universitat De Barcelona

ES 

Antoni Castells is in Spain. Castells is rated as an Elite expert by MediFind in the treatment of Familial Colorectal Cancer. He is also highly rated in 9 other conditions, according to our data. His top areas of expertise are Familial Colorectal Cancer, Lynch Syndrome, Colorectal Cancer, and Familial Adenomatous Polyposis.

 
 
 
 
Learn about our expert tiers
Learn more
Elite
Highly rated in
7
conditions

Universitat De Barcelona

Barcelona, CT, ES 

Francesc Balaguer is in Barcelona, Spain. Balaguer is rated as an Elite expert by MediFind in the treatment of Familial Colorectal Cancer. She is also highly rated in 7 other conditions, according to our data. Her top areas of expertise are Familial Colorectal Cancer, Lynch Syndrome, Familial Adenomatous Polyposis, and Colorectal Cancer.

What are the latest Familial Colorectal Cancer Clinical Trials?
Prospective Evaluation of Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy in Adult Patients
Match to trials
Find the right clinical trials for you in under a minute
Get started
Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)
What are the Latest Advances for Familial Colorectal Cancer?
Multi-Institutional Comparison of SC-TNT and LC-TNT for Rectal Cancer Non-Operative Management.
NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 1.2021.
Tired of the same old research?
Check Latest Advances
Time-dependent propensity-matched general population study of the effects of statin use on cancer risk in an interstitial lung disease and pulmonary fibrosis cohort.