A Population-based, Multicenter Cohort Study of Combined Screening for Gastrointestinal Tumors
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
To establish combined gastroenteroscopy screening and follow-up management for gastrointestinal tumors, explore and evaluate the feasibility and health economic benefits of combined screening for esophagus, stomach and colorectal cancer
Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 70
Healthy Volunteers: t
View:
• 1\. Subjects were 45 to 70 years old when enrolled 2. Willing and able to sign informed consent
Locations
Other Locations
China
Gaoyao District People's Hospital
RECRUITING
Zhaoqing
Contact Information
Primary
rong zheng
zhengrong4956@163.com
19829758242
Time Frame
Start Date: 2023-08-01
Estimated Completion Date: 2033-06-30
Participants
Target number of participants: 84000
Treatments
group one
The screening population will undergo gastroscopy, colonoscopy, fecal occult blood test (FIT), Helicobacter pylori (HP) antigen test, ring finger protein 180 (RNF180) and SEPTIN9 gene methylation test, and investigation of risk factors, including past disease history, alcohol drinking history, smoking history, tea drinking history, family history of cancer, marital and reproductive status, and dietary habits.
Group one's control（Spouse or sibling of group one )
Only the risk factors will be investigated
group two
The screening population will undergo investigation of risk factors, a fecal occult blood test (FIT), and a stool test for Helicobacter pylori (HP) antigen. If a stool occult blood test or H. pylori antigen is positive after testing, RNF180 and SEPTIN9 gene methylation testing will be scheduled. If the gene methylation test is positive, a colonoscopy will be scheduled.
group two's control（Spouse or sibling of group two)
Only the risk factors will be investigated
Related Therapeutic Areas
Sponsors
Leads: Xijing Hospital