Child-Parent Screening of Familial Hypercholesterolemia in Children
Status: Recruiting
Location: See all (6) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY
Child-parent screening for familial hypercholesterolemia has been proposed to identify children and their parent who are carrier of mutations and with high risk for inherited premature coronary artery disease. The investigators assessed the efficacy and feasibility of such screening in primary care practice. key scientific questions: 1. The 95th and 99th percentile of finger blood TC in children of 2 years old. 2. Mutations that contribute to high TC status ( serum TC \>99th percentiles) compared with international FH48 panel for FH genetic screening.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1
Maximum Age: 3
Healthy Volunteers: f
View:
• Receive routine child care
• aged 1 - 3 years old ( date of investigate minus date of birth)
Locations
Other Locations
China
Chongqin Medical University Affiliated Children's Hospital
RECRUITING
Chongqing
Anhui Provincial Children's Hospital
RECRUITING
Hefei
Qidong Women and Children Hospital
RECRUITING
Qidong
Weili Yan
RECRUITING
Shanghai
Shanxi Provincial Children's Hospital
RECRUITING
Taiyuan
Urumqi Children's Hospital
RECRUITING
Ürümqi
Contact Information
Primary
Weili Yan
yanwl@fudan.edu.cn
+86 21 64931215
Backup
Fang Liu, MD
liufang@fudan.edu.cn
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2026-09-30
Participants
Target number of participants: 15000
Related Therapeutic Areas
Sponsors
Leads: Children's Hospital of Fudan University