Familial Hypertriglyceridemia Clinical Trials

• Elevated fasting TGs and RC

• Elevated nonfasting TGs and RC

• Part A only: Fasting LDL-C ≥ 50 mg/dL (≥ 1.29 mmol/L) and ≤ 130 mg/dL (≤ 3.36 mmol/L)

• Willingness to provide informed consent and comply with the intervention and all study assessments

• Stable diet for a minimum of 3 months prior to screening and with no plans to change during screening or trial participation

• Stable drug regimen (if relevant) prior to screening visit and no planned changes after enrollment; Part B only: adjustment of lipid-lowering therapy during the diet/lifestyle run-in period is permitted