Learn About Familial Isolated Hyperparathyroidism

What is the definition of Familial Isolated Hyperparathyroidism?
Familial isolated hyperparathyroidism (FIHP) is an inherited form of primary hyperparathyroidism that is not associated with other features. In FIHP, tumors involving the parathyroid glands cause the production and release of excess parathyroid hormone, which in turn causes increased calcium in the blood (hypercalcemia). The tumors are usually benign, but a cancerous tumor can develop in rare cases. Abnormal levels of calcium cause many of the symptoms of FIHP, including kidney stones, nausea, vomiting, high blood pressure (hypertension), weakness, and fatigue. Osteoporosis often also develops. FIHP may be caused by genetic changes in the MEN1, CDC73 (also known as the HRPT2 gene), or CASR genes and is typically inherited in an autosomal dominant manner. In some cases, the cause is unknown. Genetic changes in the MEN1 and CDC73 genes cause other conditions in which hyperparathyroidism is one of many features, but some people with genetic changes in these genes have only isolated hyperparathyroidism.
Save information for later
Sign Up
What are the alternative names for Familial Isolated Hyperparathyroidism?
  • Familial isolated hyperparathyroidism
  • FIHP
  • Familial primary hyperparathyroidism
  • HRPT1
  • Hyperparathyroidism 1
  • Hyperparathyroidism, familial isolated primary
Who are the top Familial Isolated Hyperparathyroidism Local Doctors?
EP
Elena Pardi
Elite
Highly rated in
11
conditions

University Of Pisa

Department Of Clinical And Experimental Medicine, 
Pisa, IT 

Elena Pardi practices in Pisa, Italy. Pardi is rated as an Elite expert by MediFind in the treatment of Familial Isolated Hyperparathyroidism. She is also highly rated in 11 other conditions, according to our data. Her top areas of expertise are Familial Isolated Hyperparathyroidism, Parathyroid Adenoma, Hyperparathyroidism, and Parathyroid Cancer.

FS
Federica Saponaro
Elite
Highly rated in
10
conditions

University Of Pisa

Department Of Surgical, Medical And Molecular Pathology And Critical Care Medicine, 
Pisa, IT 

Federica Saponaro practices in Pisa, Italy. Saponaro is rated as an Elite expert by MediFind in the treatment of Familial Isolated Hyperparathyroidism. She is also highly rated in 10 other conditions, according to our data. Her top areas of expertise are Familial Isolated Hyperparathyroidism, Hyperparathyroidism, Parathyroid Adenoma, and Parathyroid Cancer.

 
 
 
 
Learn about our expert tiers
Learn more
CM
Claudio Marcocci
Elite
Highly rated in
29
conditions

University Of Pisa,Department Of Clinical And Experimental Medicine, Endocrinology Unit

Pisa, IT 

Claudio Marcocci practices in Pisa, Italy. Marcocci is rated as an Elite expert by MediFind in the treatment of Familial Isolated Hyperparathyroidism. He is also highly rated in 29 other conditions, according to our data. His top areas of expertise are Hyperparathyroidism, Parathyroid Adenoma, Parathyroid Cancer, Hypercalcemia, and Hormone Replacement Therapy (HRT).

View All Doctors
What are the latest Familial Isolated Hyperparathyroidism Clinical Trials?
Match to trials
Find the right clinical trials for you in under a minute
Get started
View All Clinical Trials
Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Familial Isolated Hyperparathyroidism?
A Woman with a 27-Year History of Hyperparathyroidism and Hypercalcemia Who Was Diagnosed with Low-Grade Parathyroid Carcinoma.
Condition: Woman with 27-Year History of Hyperparathyroidism and Hypercalcemia with Low-Grade Parathyroid Carcinoma (PC)
Journal: The American journal of case reports
Treatment Used: Surgery, Radiotherapy, and Pharmacological Treatment
Number of Patients: 1
Published: March 12, 2021
Tired of the same old research?
Check Latest Advances
View All Latest Advances