What is the definition of Familial Multiple Lipomatosis?

Familial multiple lipomatosis (FML) is a rare condition that is characterized by multiple lipomas on the trunk and extremities. As the name suggests, FML is diagnosed when multiple lipomatosis occurs in more than one family member, often over several generations. The lipomas associated with FML are usually painless, but may impact quality of life as they can be numerous and large. Although the condition appears to be passed down through families in an autosomal dominant manner, the underlying genetic cause is currently unknown. Treatment is based on the signs and symptoms present in each person. Surgical excision may be necessary if the tumors interfere with movement and/or daily life.

What are the alternative names for Familial Multiple Lipomatosis?

  • Multiple lipomatosis
  • Condition: Lumbar Spinal Stenosis Combined with Obesity-Induced Idiopathic Spinal Epidural Lipomatosis
  • Journal: BMC surgery
  • Treatment Used: Posterior Lumbar Fusion
  • Number of Patients: 1
  • Published —
This study reports a case of a 53-year-old man with lumbar spinal stenosis combined with obesity-induced idiopathic spinal epidural lipomatosis treated with posterior lumbar fusion.
  • Journal: Journal of surgical orthopaedic advances
  • Published —
Bilateral Nerve Involvement in Lipomatosis of Nerve.
Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 3
  • Intervention Type: Drug
  • Participants: 1
  • Start Date: June 1, 2021
Hydrocortisone Treatment for Symmetric Lipomatosis Associated With Neuropathy (SLN): an N-of-1 Study
Clinical Trial
  • Status: Recruiting
  • Intervention Type: Diagnostic Test, Other, Device
  • Participants: 60
  • Start Date: January 10, 2020
Endocrine Diabetes Screening in Patients With Shwachman-Diamond Syndrome DIABETES/ ENDOCRINE SURVEILLANCE IN SDS