Familial Paroxysmal Nonkinesigenic DyskinesiaSymptoms, Doctors, Treatments, Advances & More
Learn About Familial Paroxysmal Nonkinesigenic Dyskinesia
Familial paroxysmal nonkinesigenic dyskinesia is a disorder of the nervous system that causes episodes of involuntary movement. Paroxysmal indicates that the abnormal movements come and go over time. Nonkinesigenic means that episodes are not triggered by sudden movement. Dyskinesia broadly refers to involuntary movement of the body.
Mutations in the PNKD gene can cause familial paroxysmal nonkinesigenic dyskinesia. The function of the protein produced from the PNKD gene is unknown, although it is thought to play an important role in normal brain function. The PNKD protein may help control the release of chemicals in the brain called neurotransmitters, which allow nerve cells (neurons) to communicate with each other.
Familial paroxysmal nonkinesigenic dyskinesia is a very rare disorder. Its prevalence is estimated to be 1 in 5 million people.
This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is typically sufficient to cause the disorder. In all reported cases caused by PNKD gene mutations, an affected person has inherited the mutation from one parent. A small number of people with the altered gene have not developed signs and symptoms of the condition, a situation known as reduced penetrance.
St. Vincent Neurosurgery
Javier Echeverri is a Neurologist practicing medicine in Billings, Montana. He has been practicing medicine for over 47 years. Dr. Echeverri is rated as an Advanced provider by MediFind in the treatment of Familial Paroxysmal Nonkinesigenic Dyskinesia. He is also highly rated in 26 other conditions, according to our data. His clinical expertise encompasses Essential Tremor, Parkinson's Disease, Movement Disorders, Epilepsy with Myoclonic-Atonic Seizures, and Deep Brain Stimulation. Dr. Echeverri is currently accepting new patients.
Atrium Health Neurology Specialty Care, A Facility Of Carolinas Medical Center
Danielle Doggett is a Neurologist practicing medicine in Charlotte, North Carolina. Dr. Doggett is rated as an Advanced provider by MediFind in the treatment of Familial Paroxysmal Nonkinesigenic Dyskinesia. She is also highly rated in 19 other conditions, according to our data. Her clinical expertise encompasses Parkinson's Disease, Movement Disorders, Essential Tremor, Drug Induced Dyskinesia, and Deep Brain Stimulation. Dr. Doggett is board certified in American Board Of Psychiatry And Neurology. Dr. Doggett is currently accepting new patients.
Aurora Neuroscience Innovation
Taylor Finseth is a Neurologist practicing medicine in Milwaukee, Wisconsin. Dr. Finseth is rated as an Advanced provider by MediFind in the treatment of Familial Paroxysmal Nonkinesigenic Dyskinesia. He is also highly rated in 24 other conditions, according to our data. His clinical expertise encompasses Camptocormism, Parkinson's Disease, Movement Disorders, and Conversion Disorder. Dr. Finseth is board certified in American Board Of Psychiatry & Neurology.
Published Date: August 01, 2017
Published By: National Institutes of Health